I recently switched from a 1000 mg metformin tablet broken in half taken at breakfast and dinner to 500 mg metformin tablet taken at breakfast and dinner. I have been surprised by side effects that I experienced when I first took met (especially gas - - embarrasing!) occuring after this change. Could there actually be a difference between breaking a 1000 mg tablet vs. taking a 500 mg tablet? These are not extended release.
im not sure hun. i just started my met 500mg 4 days ago and each day goes by ive been feeling sleep and gassy and some poo's (tmi) lol but my bowls arent the best anyways. after a week on 500mg i go to 1000mg for a week and then 3rd week i go to 1500mg until further notice. im just hopeing once it gets into my system better i will start feeling better. today ive just layed around not feeling like doing anything really but i pray it gets better over time! take care and good luck <3
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Are they XR? As far as I know the XR ones should not be broken...
Other than that, the only difference I can think of between half of a 1000mg and a whole 500 mg would be that you might lose a little bit when you cut them in half. Even with a pill slicer (or whatever the technical term is), you lose some "pill dust", KWIM?
That's all I can think of is that you were getting a little less than 500mg when you were cutting them, so your body feels like your dose has gone up, and is adjusting... Does that make sense?
When I first started taking Met my doctor started me out slowly, first by taking 250, 500, 750, 1000 then finally 1500mgs a day. So I had to cut my pills to get the correct dosage. I didn't find that it affected anything, and my doctor and pharmacist were well aware I was doing this. If your still concerned you should give your pharmacist or doctor a call.
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Carrie
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I'm taking 1500mg/day, and to save money and time, I've been cutting my 1000mg pills in half. I haven't noticed any difference vs when I was taking a 1000mg + a 500mg pill.
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Me-27 To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts. DH-32
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Dx: 10/07 Met: 2000mg
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1000 mg tablets in half vs. 500 mg tablets 
- embarrasing!) occuring after this change. Could there actually be a difference between breaking a 1000 mg tablet vs. taking a 500 mg tablet? These are not extended release.
