When I was first diagnosed with PCOS, my labs came back with elevated ALT/AST levels. I was referred to a liver specialist at University of Cincinnati hospital. My hep specialist said there is a really strong connection between PCOS sufferers and fatty liver. He supports the theory of Metformin actually helping the condition. I take 1000mg twice daily. He also said that modest weight loss of 10% of weight (from the time of diagnosis) often causes enzyme levels to normalize. Additionally, I take 800 IU of Vitamin E daily (natural vitamin E supposedly is more effective than synthetic), along with 1250 mg of Urso (also known as actigall or ursodiol), which decreases the amount of cholesterol produced in the liver, thus decreasing the amount of fat in the liver. It is normally given to patients with gallstones, but my doc has had much success using it to treat his patients with fatty liver. Originally, my numbers were 110 AST/84 ALT - they are now 40 AST/24 ALT. Hope this helps!!! |