I was very interested to see this thread because as of today my liver enzymes (AST & ALT) are finally officially NORMAL again!!! yippee! My enzymes were slowly going up and in July 2003 when I finally got up to 2000mg of metformin they went through the roof! My doctors (endo and gasteroenterolgist) didn't believe me that it was the metformin and kept blaming it on my weight.... they were pushing me to do a liver bioposy (didn't sound fun to me) so I got a new Doc (gastroenterologist (sp)). He agreed to let me wait three months and come back for more tests. Today I got the test results and everything was great! Funny thing was that the last gastro had said I had fatty liver based on an ultrasound but this time I had a GGT test which my current doc said is a more sensitive way of testing for fatty liver and it came back fine! Phew! I know that is a lot that I have said... but I am just so happy all is good now! The only thing I did to help is some naturopathic treatments (I can tell you more if you want to know).
Anyway I just know that for me Metformin seemed to cause my elevated liver enzymes..... and I am glad now that they are back to normal!
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Jennifer in Seattle
Currently taking Actos, Armour, Byetta and a bunch of topical acne medications! |