I've seen several reports of the effect of simvastatin on testosterone, but none on other statins. The evidence on pravastatin is sketchy...some say it's there, some don't. However, I'd expect that we may eventually find this effect in other statins because hormones (testosterone included) are made from cholesterol. If you get rid of the excess cholesterol in your body, it makes sense that you wouldn't have as many hormones either.
Has anyone had any luck with cholesterol and/or PCOS symptoms on any of the statins? I am on my third lipid-lowering drug (tried Lipitor, Lopid, and now Pravachol) and Pravachol is the only one that seems to be working for me and that I can tolerate. It just isn't bringing my numbers down enough, so I may have to either go on a different drug or a higher dose of this one. But I haven't really noticed much of a difference in PCOS symptoms after about three months on pravastatin.
btw, if anyone else is taking pravastatin (Pravachol)--its patent expires this month, so it should be going generic soon! |