I've noticed weight loss within a couple of weeks of taking Metformin. I've stopped and started it probably about 3 times for various reasons. Each time when I go off, I go back to REALLY craving bad foods and end up gaining weight. Usually after about a week of taking it, (I've started back recently, trying to build myself up to 2000mg but now at 500mg, around 4pm (I work 8am-noon, come home for a 4 hour lunch and return to work from 4-8pm) and I can usually hold off the diarrhea until I get home. Sometimes it works, sometimes it doesn't. I just can't stand to wake up in the middle of the night to have to run to the bathroom because then it takes me forever to get back to sleep. Kinda sucks because I work in a call center and I HAVE to be on the phone constantly to take incoming calls and they're really strict about only going to the bathroom/get drinks or snacks on breaks only. So yeah, it makes it a little difficult but this seems to work best for me right now.
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