The biggest things to not mix with your thyroid supplement is calcium and Vitamin C (so it's easiest/most convenient to simply stay away from all vitamins). If you take your thyroid in the morning, try to avoid having milk/dairy for breakfast.
The regime I do is as follows: 2/3 of my prescribed dosage of Thyroid (Armour) and fish oil supplement when I wake up (6am). Multivitamin, calcium supplement, B complex, Vitamin D with lunch (11am). Remaining 1/3 of Thyroid on the way home from work (5pm).
Seems to work the best for me, and my doctor approves.
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