PCOS Message Board - View Single Post - Nizoral shampoo to help with hairloss (Nizoral is a otc dandruff shampoo)

Kora · 08-27-2009, 05:53 PM

This study was done on men but includes ketoconazole

Quote:

Titre du document / Document title
Comparative efficacy of various treatment regimens for androgenetic alopecia in menAuteur(s) / Author(s)

KHANDPUR Sujay ; SUMAN Mansi ; BELUM SIVANAGI REDDY ; Résumé / Abstract

Our understanding of the aetiology of androgenetic alopecia (AGA) has substantially increased in recent years. As a result, several treatment modalities have been tried with promising results especially in early stages ofAGA. However, as far as has been ascertained, there is no comprehensive study comparing the efficacy of these agents alone and in combination with each other. One hundered male patients with AGA of Hamilton grades II to IV were enrolled in an open, randomized, parallel-group study, designed to evaluate and compare the efficacy of oral finasteride (1 mg per day), topical 2% minoxidil solution and topical 2% ketoconazole shampoo alone and in combination. They were randomized into four groups. Group I (30 patients) was administered oral finasteride, Group II (36 patients) was given a combination of finasteride and topical minoxidil, Group III (24 patients) applied minoxidil alone and Group IV (10 patients) was administered finasteride with topical ketoconazole. Treatment efficacy was assessed on the basis of patient and physician assessment scores and global photographic review during the study period of one year. At the end of one year, hair growth was observed in all the groups with best results recorded with a combination of finasteride and minoxidil (Group II) followed by groups IV, I and III. Subjects receiving finasteride alone or in combination with minoxidil or ketoconazole showed statistically significant improvement (p<0.05) over minoxidil only recipients. No signifcant side-effects related to the drugs were observed. In conclusion, it is inferred that the therapeutic efficacy is enhanced by combining the two drugs acting on different aetiological aspects of AGA.Revue / Journal Title

Journal of dermatology ISSN 0385-2407 Source / Source

2002, vol. 29, n^o8, pp. 489-498 [10 page(s) (article)]Langue / Language

Anglais
Editeur / Publisher

Blackwell Publishing, Carlton, AUSTRALIE (1974) (Revue)
Localisation / Location

INIST-CNRS, Cote INIST : 2353 B, 35400010211259.0040