When I was in college I was taken off of my spironalactone and put on Prednisone (sp?) which was REALLY stupid of my doctor. I ended up gaining 30 pounds in about 5 months and my anger/aggression shot through the roof. I was mess. I felt like I was living in some kind of anger cloud and the littlest things could set me off. I am normally a peaceful, loving person, and at this time in my life I was to the point where I would punch cement walls, slam my hands down on tables, kick things, etc. (I was never physical with a person, just with inanimate objects when I was alone and angry.) It wasn't me at all, but at the time, my testosterone level was so high (higher than my dad's!) that I was entirely out of control. My then girlfriend, whom I lived with, later told me that I was so angry all the time that she actually had a plan in place to move out and live with her best friend if I got any worse. I couldn't believe it when she told me that because it felt like proof that I had been a monster and that I was so far from my real self then.
I finally went to a GOOD doctor who told me that prednisone was the last thing I should have been put on and put me back on my spironalactone. Immediately, I felt the cloud of anger melt away and I was back in the real world. It was amazing. Now, when my PCOS flares up or if I'm having PMS, I can feel some of that old mood swing/aggression coming back, but I am much more aware of it. I have a heavy bag that I take my anger out on now, instead of cement walls. Exercise really reduces all of that negative energy.
Has anyone else had this experience with prednisone...or just with anger/aggression in general?
I have definately had this experience with anger and aggression. It was like the the littlest things would set me off on an anger frenzy. My poor husband bore the brunt of it. The crazy thing was that half of the time I wold not even be aware of my behavior unless it was pointed out to me. I found that getting on the right BC really helped me wiht this issue.
Lol, my boyfriend's ready to kill me because I'm so angry and aggressive at the moment. And the worst part is, until I've calmed down (about 3 hours later lol) I don't realise how much of an idiot I'm being. I've thrown things and kicked things and just acted a bit pyschotic really, when a couple of years ago I'd never have dreamed of doing those things. Now, someone only has to look at me the wrong way and I'm off on one. I blame my BC to be honest. I'm glad you're feeling more normal now though!
this reply is a couple of weeks late, but i am beginning to suspect that i am experiencing something similar. my insurance changed in the fall and i got a new endocrinologist who took me off the spironolactone i was taking for years because of the mouse carcinogenicity studies and refuses to put me back on it despite that i've experienced a variety of adverse symptoms since discontinuing the spiro. i've been flying off the handle a lot lately, and i'm thinking that it's me, not circumstance. since i can't go back on the spironolactone without a prescription, what else can i do to attenuate the aggression and mood swings? do you ladies have any tips, having been through something similar? thank you in advance.
Just thought i'd put my two cents worth in .. I was put on androcur along with dianette for a few months and had to be taken off the androcur because I was like a one woman circus. I was irritable angry sad, crying the next minute over nothing it was terrible my poor bf I don't know how he didn't run a mile. Am I alone in saying that it's a lot of guess work with some doctors oh that didn't work try this?
I wish more people would comment on this post. I had anger problems literally since I was about 3 to the point where family members wouldn't babysit for me and my mom / grandma looked into getting me an exorcism (they deny this now, but my mom told me once -- looking back we think that relates to my awful migranes my kiddie temper lol). It got better when I was 16 and started birth control to control my never ending periods (I'm part of the "unusual" group that always has their period instead of never getting it). It pretty much spiraled out of control again when I switched BCP's and then went on anti-anxiety meds... I'm worried that I won't ever be fully able to control my anger and when I bring it up to my doctors they say to go to anger management.
I honestly do not know what to do about the anger problem, but I feel it has to be PCOS related but any suggestions of medication or other ways to get your doctors to listen would seriously be appreciated.
I too have had irritability and anger issues. Totally unlike me. I was always knows as a peaceful person, and everyone I knew over the years told me I had more patience than anyone they knew. Then things changed over the last couple of years. I got angry for no reason, little things would send me over the edge. I just saw my endo and my progesterone is extremely low--in the range of a post-menopausal woman (I'm 32--no menopause here). He told me before the testing that it sounded like a progesterone deficiency, because that can cause extreme moodiness and irritability. Add to that my high testosterone, because that causes irritability, too, and you have the makings of the near-monster I have become! Have your hormones checked if you haven't already. This endo blends eastern and western meds, and he prescribes bioidentical hormones, not the synthetic stuff, so I will be starting on that as soon as it gets shipped to me, and we'll see if I can get back to the old me soon.
I have very bad mood swings and they seem to come and go throughout the day. When I was on Metformin they seem to happen less frequently, but my Dr. dosent seem to think that I need it. So I am looking to go to a diferent Dr. so that I can get it again to get my sanity back LOL.
I have about 4 or 5 mood swings a day! I really hate taking it out on my family and friends, especially my older sister she tries her hardest to not say or do anything but her patience is running out BIG time. My parents says that the demons are trying to take over me (My parents are christans) but I don't think so.... I think it has something to do with the PCOS, I have a crease on the top of my forehead (it's small no one claims they see it) I don't think a guy could put up with my regularly mood swings lol<3
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I am new to this board. Found it a few years ago and now I am back. I am dealing with major moods several times a day and it is soooo not me. I am trying to be patient and do as my doctor says and what my wallet will allow. I have PCOS and had a tubal pregnancy almost 2 yrs ago (october). I feel like since then that my hormones are really out of wack. Not many people understand me and I try to keep it to myself. My hubby really catches it ALL! I am trying and that's all I can do!
Well of course when your testosterone and or other hormones are off you are going to be easily angered.
When I am on metformin I have no anger problems but when i´m not on it...wow the two weeks before my period are a nightmare. I had to be taken off the metformin unfortunately because I was experiencing bladder problems form the metformin. I was prescribed Androcur (not available in the US).
I will say that many women are diagnosed with bi-polar or depression who I´m certain have hormone imbalances. Also, if your hormones remain unbalanced it can cause a chemical imbalance in the brain...those chemical imbalances are mental health disorders.
I worked as a psychologist in a psychiatric hospital for 4 years and what I saw everyday were women diagnosed and medicated for bi-polar and other mental illnesses. The medications they are given have ALOT of side effects. I always suggested to the females I worked with is get your hormones checked by an endocrinologist.... Alot of the women thought that if their gyno or general doctor did a quick thyroid test and it came back in ¨normal range¨they were fine. I had to explain that they had to test their hormone levels like testosterone and a true thyroid test involves going to the hospital and it takes several hours. They inject a die and withdraw blood at 45 minute intervals. I´m in ¨normal range¨according to the quick blood test, but that isn´t normal for me. Without meds I lose my hair, am tired, and have all the side effects of hypothyroidism.
I truly believe my mother had a hormone imbalance that was never properly diagnosed. After many years of her life without treatment, she began having serious mental illnesses like bi-polar, and eventually turned to drugs to self medicate.
Imagine if more women were better educated! We have millions of women suffering from the severe side effects of psychiatric drugs ...such as fibromyalgia, miagranes, depression, etc....and these side effects don´t go away when you stop taking psychiatric drugs...these drugs permanently alter the chemical balance of the brain! What if all they needed was their testosterone level lowered? or thyroid function improved?
Feedback anyone? Love to hear your stories....
These are exactly the types of issues that I want to do my dissertation on. I am a PsyD student in my third year of school. I don't believe these issues are even close to being well researched and many times they go unacknowledged by M.D.'s and Mental Health Professionals alike.
Aggression/Mood Swings 
