I found some natural combats for the article below - google 'em for yourself:
myo-inositol, d-chiro-inocitol & pinitol which is found in
greens, soy, beans, cantaloup, pumpkin extract and buckwheat, etc. ( I have
red wines w/ muscadine grapes written down here, but I don't know if that is
included in there, but it must be good for you or I wouldn't have written it
down...I think it's antifungal and found in wine - yeah.) I also came across an herb college which listed ways to reduce ghrelin
which improves leptin, here they are:
Cayenne pepper - few drops before every meal
Dandelion roots
Algin & Pectin
Gymnema - recommended for those who crave sweets, apparently it destroys
ability to taste sweets and lasts for 20 minutes.
Here's some other herbals I found at various sites that are supposed to help,
too:
PQQ - pyrroloquinoline quinone
Selenium - 200 mg
Carnitine
Inositol - B8
N-Acetyle-Cystein - amino acid drops
Pleurisy root - for inflammation
Asian Ginseng - lowers blood sugar
Ginko lower blood sugar & blood thinner
I3C - anticarcenogin and improves liver function- naturally in cabbage,
broccoli, brussel sprouts
Queretin - found in capers, apples, tea, Camellia, red grapes, citrus &
broccoli
DIM - found in broccoli & cauliflour
Of all my research the most relevant foods that kept coming up over and over
were broccoli, apples, pumpkin and grains particularly buckwheat.
http://www.weightlossadviser.com/fat-cell-hormones.htm
There's more to the article, but this was the most informative to me:
Leptin. When you gain weight, the fat cells release more leptin, which should make you eat less and burn more calories. But, the more fat you accumulate, the less effective leptin becomes. When you lose weight, the cells release less leptin. That makes you want to eat more and makes it difficult to keep off the weight you have lost.
Adiponectin. This hormone helps insulin pull sugar from the bloodstream into the cells, where it is used for fuel or stored as glycogen. The more fat you have, however, the less adiponectin your fat cells secrete. This is probably part of the answer to insulin resistance and the development of type 2 diabetes.
Inflammatory proteins. Fat cells can release proteins (interleukin-6 and tumor necrosis factor-alpha) that cause low-level inflammation throughout the body. The inflammation is too subtle to produce fever or pain, but it still causes trouble. Inflammation encourages the rupture of atherosclerotic plaques which have formed in blood vessels, leading to a heart attack or stroke.
Ghrelin. This strangely spelled hormone is released by the stomach when you lose weight. It makes you hungry and want to eat more, so it is tougher to keep the weight off. A vaccine is now being tested that consists of an antibody against ghrelin (as of May 2005).
Another informative link on fat cell hormones 
