Is anybody on Met who is not IR?

isisunveiled · 08-12-2002, 12:47 PM

I have heard that some Dr's are giving Met to patients that are not IR. Also, I had my gluc to insulin ratio and it was great! My gluc level was 91!! I'm usually hypoglycemic. I hardly ever get a reading like that. So, because of the test results, met was taken off the game plan. I was actually disappointed because I heard so many good things about it. Can anyone give any input on this?

Mary

pcc10012 · 08-12-2002, 07:48 PM

Hi Mary,

When I first visited my RE, I really wanted to try Met because I thought it would be good treatment for my PCOS and help me ttc. She did bloodwork and my fasting insulin came back normal, so she was reluctant to try the Met and did not prescribe it for me. Since I am relatively thin, she didn't think I was IR also just by looking at me.

But two failed clomid cycles later, she put me on the Met. She said she had recently been to a conference and heard many good things about using it for treatment.

I have not had a GTT and I know that it would be a better indicator of IR. I've read that all women with PCOS are IR to some degree, however small, and so it seems that many of us could benefit from Met.

Good luck~~~You may want to try finding another doctor that will give the Met a chance or else look for some studies showing the benefits of Met for non-IR PCOSers and show them to your doctor.

Best,
pc

Lilly · 08-12-2002, 09:42 PM

I am on grams of met a day and I am not IR.

Lilly 31
DH 31
ttc#2 for over 4 years

Lilly · 08-12-2002, 09:45 PM

I meant to say that I am on 2000 mg. or 2 grams a day.

LSGMSU1 · 08-12-2002, 09:53 PM

There is a good article on met with normal labs in Thin Cysters in the post about thin cysters and met experiences you may want to check out. I've printed this out and am going to take this to my endo to see if that will convince her to give me a legitimate Rx. If not, I am going to try another Dr. Ironically, if I hadn't decided to improve myself and successfully lose 30 lbs, I would have tested IR and got the met w/o a problem. But since the weight loss, my labs have been normal.

ssivakami · 08-13-2002, 07:30 AM

LSGMSU1 is right. There are studies which indicate that Met helps lower male hormone levels and brings about regular ovulation in thinner cysters too.

My BMI has always been normal ... 23-24 range. And so my gynaec has prescribed me with only 500 mg Met per day. I've been on it for 4 months now. It has made me lose a few Pounds, but my cycles are regular, if a bit long-ish (40-50 days).

BTW I recently met my gynaec again with a print-out of that thin cysters and Met article. Surprisingly (or maybe I'd just become a little cynical after reading the experiences of many cysters here!), she seemed very open to the idea. She read the article carefully, twice ... and showed it to her assistants (a couple of them are always around when she checks patients).
But then she said that those studies were conducted on American women (who are, on an average, bigger and heavier) and would not be valid for Indian women. Type II Diabetics in India are also not prescribed more than 1000 mg per day. She says many of her patients who she has prescribed 1000 mg Met to complain of weakness and fatigue and she's had to reduce the dosage to 500 mg.
She asked me to take a few tests - blood sugar and serum prolactin. My prolactin levels have been a little on the higher side in the past, and she'd prescribed B-Long (Pyridoxine Hydrochloride) tablets ... which also worked well. I'm hypothyroid and that means my prolactin levels tend to go high and that also inhibits ovulation. She's asked me to come see her with the test results - which I plan to do in a day or two.
But she seems open to increasing dosage and I'm glad that my gynaec is so open minded

- S.