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Old 10-19-2008, 11:35 PM   #1 (permalink)
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Default (APS) Antiphospholipid Syndrome

If anyone knows something about APS...
looking for some info. I posted this on fertility friend, but wanted to pose this question here too.

I'm going to bring this up with my doctor tomorrow and ask, but I wanted some other opinions.

My sister has APS, and had to take BA for her second pregnancy (Her first pregnancy was a stillbirth at almost 42 weeks due to a clot in the cord.) with her third pregnancy she had to take Heparin because her results came back much worse. She almost lost that pregnancy at 16 weeks, but she also was Rh- and desensitized to her roghram (sp?) shot.

I read that they aren't sure if it's hereditary, that it may be, but it may not. I'm Rh+, not - like her. We also have different fathers.

Do you think my doctor should test me for it, just based on the fact that she has it? Like I said, I'm going to ask them tomorrow when I go in to check follicles, but I wanted to see what you ladies think. I don't want to take any risks if I can help it, but I also know my doctor is not the type to run any tests he thinks are unnecessary.

But I am obviously a little concerned here.

What do you ladies think?
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Old 10-20-2008, 01:28 AM   #2 (permalink)
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It might not be a bad idea-I had a bunch of labwork done last week to see if I have any clotting issues and haven't heard back on them yet. I've read that APS is the only acquired clotting disorder as opposed to all the inherited ones, though. And the Rh issue is a whole other boatload of issues, at least you don't have to worry about that.
But I think you do have a reason to be concerned and it wouldn't hurt to ask.
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Old 10-23-2008, 07:57 PM   #3 (permalink)
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Default pregnancy mentioned!

Hi there, I was diagnosed with APS after losing my twins at 22 weeks, I fell pregnant again in March this year and started aspirin just after my bfp with a view to start lovenox injections once a heartbeat had been seen, sadly didn't get that far and m/c at 7 weeks.
After that I was put on aspirin all the time and got a bfp in July, started injections straight away and fingers crossed we're still hanging in there!!

I'd certainly ask about getting tested as your sister has it, my sister has been diagnosed with pcos and is thinking of ttc and she's going to ask to be tested for it to, I'd hate for her to go through the losses I have if it's at all preventable.
APS often only shows itself with m/c and no other symptoms (like thrombosis etc)

good luck and I hope you can get checked out.
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Old 10-23-2008, 08:24 PM   #4 (permalink)
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Thanks ladies My doc ordered the test, I just need to find the time to go in and get it done.
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Old 11-05-2008, 01:52 AM   #5 (permalink)
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Yep. Get tested. All of the women in my family have had miscarriages, believed to be in part due to APS (or Anticardiolipin Antibody Syndrome). I'm 16w pregnant with my first... thankfully, no problems thus far. But you should tell your docs as they'll likely want to test your antibody levels (I really don't understand it all). My uncle had a heart attack in his 40's... long story short, this is how we found out about this disorder/syndrome. Sidenote: the family members of mine who have this test positive for Lupus but do not actually have Lupus... it's just another auto-immune disease.
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