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Old 08-14-2009, 06:36 PM   #1 (permalink)
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Lightbulb Article: PCOS link to Autoimmune Thyroiditis

Just wanted to pass along some further insight regarding the connection between PCOS and autoimmune thyroiditis. A link to the full article is listed below. But, I find this particular part so compelling:

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Women are known to have a 5- to 10- fold greater incidence of organ-specific autoimmune diseases than men. This raises the possibility that female hormones might play a pathogenic role in such disease. It's particularly intriguing that the incidence of autoimmune thyroiditis is known to be roughly twice as great during perimenopause--a time of low progesterone and substantial estrogen-as in the reproductive years. Low progesterone is also a hallmark of anovulatory women with PCOS.

These observations raise a testable hypothesis: Perhaps administration of progesterone or progesterone derivatives that specifically target immunocompetent cells might prevent autoimmune thyroiditis in women with PCOS, Dr. Gaertner said.
http://findarticles.com/p/articles/m...6/ai_81006734/
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Old 08-20-2009, 08:52 PM   #2 (permalink)
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Very interesting! Thanks!
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Old 08-23-2009, 11:52 PM   #3 (permalink)
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WOW That IS interesting. Thanks!
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