Friday 27 October 2006
Endometriosis does not increase bone fracture risk
Source: Fertility and Sterility 2006; Advance online publication
Determining whether women with pelvic endometriosis are at increased fracture risk.
Women with pelvic endometriosis do not appear to have increased fracture risk, study findings show.
Most research into bone mass and fracture risk has focused on diet and exercise, although a small number of studies have also linked bone mass with menstrual disorders, iIn particular endometriosis or its treatment.
To investigate this issue further, Joseph Melton, from the Mayo Clinic in Rochester, Minnesota, USA, and co-workers analyzed the incidence of bone fracture among 987 women with endometriosis over a 19-year period. All women were from the general population.
During this time, 256 women suffered 449 fractures, although the cumulative incidence of fractures was not elevated compared with the level expected, at 30.8 percent versus 30.6 percent, respectively.
Fracture risk increased with age (hazards ratio [HR]=1.61), corticosteroid use (HR=2.78), prior hip, spine, or forearm fracture (HR=1.82), and the use of selective estrogen receptor modulators such as tamoxifen (HR=4.34).
“These are the only data that quantify the risk of all types of fracture associated with documented endometriosis, and they indicate that long-term fracture risk is not a particular concern for most community women with this condition,” Melton et al conclude.
Posted: 26 October 2006
http://www.orgyn.com/en/news/2006/We...90170651851852
Endometriosis does not increase bone fracture risk 
