Endothelial Dysfunction in Polycystic Ovary Syndrome
Greek research finds endothelial dysfunction in young female patients with polycystic ovary syndrome (PCOS). PCOS, increases a woman's risk for developing diabetes and cardiovascular disease, include excess hair growth, irregular menstruation and central body obesity.
Endothelial dysfunction, which is caused by disease and environmental factors, such as smoking, occurs when the normal biochemical process in the cells lining blood vessels fail to work properly.
The purpose of the study was to investigate the relationship between markers of endothelial activation, low-grade chronic inflammation and endothelial dysfunction in young women with PCOS. The study involved 25 PCOS women between the ages of 25 and 64 as well as 25 control women. Endothelial function was assessed by flow-mediated dilatation on the brachial artery and by ET-1 plasma levels.
Dr. Evanthia Diamanti-Kandarakis of the Laiko University Hospital, Medical School of Athens, Greece said, "One of the culprits of PCOS may not only be endothelial dysfunction but its association with low-grade chronic inflammatory markers and metabolic and hormonal aberrations."
Source:
http://biz.yahoo.com/prnews/050607/dctu020a.html?.v=1
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Endothelial Dysfunction in Polycystic Ovary Syndrome increases risk of diabetes 
