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Old 05-19-2004, 12:21 AM   #1 (permalink)
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Default FDA revision Metformin HCl and XR Tablets Not Associated With Lactic Acidosis

Someone posted this on another board, but there was no link to go along with it (and I couldn't find anything else about it):


Metformin HCl (Glucophage) and Metformin HCl Extended Release (Glucophage XR) Tablets Not Associated With Lactic Acidosis

The FDA approved a revision on March 19 to the warnings section of labeling for metformin HCl (Glucophage), and metformin HCl extended release tablets (Glucophage XR), both of which are made by Bristol-Myers Squibb, to reflect that there were no reports of lactic acidosis during more than 20,000 patient-years of exposure to metformin in clinical trials.
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Met 2000mg since 2001, started Glucophage XR 4/22/04, then switched to Met ER 6/04; also: multi, Vit. C, Vit. E, B12/folic acid combo, fish oil & borage oil combo, garlic capsules, cinnamon, Vitex, calcium with magnesium/zinc, biotin, CoQ10, selenium,iron
Other meds: Verapamil and Altace(for blood pressure)
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Old 05-19-2004, 04:42 PM   #2 (permalink)
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I can confirm this:

FDA Safety Labeling Changes: http://www.medscape.com/viewarticle/474836
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