Emmanuelle

For those of you still waiting for d-chiro-inositol, there is a very good supplement on the market called Glucorell R which is the pure, natural version of alpha-lipoic acid.

R Lipoic Acid is said to be many times more effective than what is currently sold on the market today as alpha-lipoic acid which is a mixture of 50% natural lipoic acid with 50% synthetic lipoic acid. Glucorell R is the 100% pure form and it seems to be extremely promising for diabetes, insulin resistance and general weight management.

It allows you to process carbs much more effectively without following a strict low-carb diet. Here's the website for anyone interested: www.glucorell.com

lovedlux

...but of course it does coming from a site that sells it. so have you tried this glucorell? if so how long have you been taking it and with what results? thanx for the info.

__________________
Every second is another chance to turn it all around--Vanilla Sky(movie)

KC1

1: FASEB J. 1999 Feb;13(2):411-8. Related Articles, Links


(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate.

Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB.

Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.

A diet supplemented with (R)-lipoic acid, a mitochondrial coenzyme, was fed to old rats to determine its efficacy in reversing the decline in metabolism seen with age. Young (3 to 5 months) and old (24 to 26 months) rats were fed an AIN-93M diet with or without (R)-lipoic acid (0.5% w/w) for 2 wk, killed, and their liver parenchymal cells were isolated. Hepatocytes from untreated old rats vs. young controls had significantly lower oxygen consumption (P<0. 03) and mitochondrial membrane potential. (R)-Lipoic acid supplementation reversed the age-related decline in O2 consumption and increased (P<0.03) mitochondrial membrane potential. Ambulatory activity, a measure of general metabolic activity, was almost threefold lower in untreated old rats vs. controls, but this decline was reversed (P<0.005) in old rats fed (R)-lipoic acid. The increase of oxidants with age, as measured by the fluorescence produced on oxidizing 2',7'-dichlorofluorescin, was significantly lowered in (R)-lipoic acid supplemented old rats (P<0.01). Malondialdehyde (MDA) levels, an indicator of lipid peroxidation, were increased fivefold with age in cells from unsupplemented rats. Feeding rats the (R)-lipoic acid diet reduced MDA levels markedly (P<0.01). Both glutathione and ascorbic acid levels declined in hepatocytes with age, but their loss was completely reversed with (R)-lipoic acid supplementation. Thus, (R)-lipoic acid supplementation improves indices of metabolic activity as well as lowers oxidative stress and damage evident in aging.

PMID: 9973329 [PubMed - indexed for MEDLINE]