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Old 11-13-2005, 10:44 PM   #1 (permalink)
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Question Glucose to Insulin Ration

A year ago I was dx'd with IR. My numbers are as follows:

Fasting Glucose 99 (within normal limits)

Fasting Insulin 25 (within normal limits)

Fasting Glucose to Insulin Ration 3.96 (Shows IR as it's less than 4.5)

Is this right? What exactly does it mean?
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Old 11-15-2005, 11:36 PM   #2 (permalink)
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Anyone?
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Old 11-16-2005, 06:56 AM   #3 (permalink)
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Sorry Torie I wish I knew the answer, I was just dx'd w/ diabetes and don't know a whole lot yet....

I hope this bumps it so someone else sees it!!

Good Luck,
Julie
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Old 11-16-2005, 01:13 PM   #4 (permalink)
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There are several different ways that IR can be evaluated, and the GI ratio is one of them. Here's some info:

Prior to progression to IGT or type 2 diabetes, however, there isn't a universally agreed upon simple lab test to screen for IR. In the research setting, detection of IR usually involves IV infusions, multiple blood draws, and complex analysis ("clamp technique"); it is clinically impractical. A pragmatic, clinical approach to the diagnosis of IR is to perform a 75 gram oral glucose tolerance test, measuring fasting and 2 hour glucose levels. By this approach, IGT or type 2 diabetes may be revealed, proving advanced insulin resistance. Short of this, IR may be suggested by an elevated fasting insulin level (>20 microU/mL), a reduced fasting glucose / insulin ratio (G/I < 4.5), or an elevated 2 hour insulin level following a 75-gram glucose load. However, there aren't well-established criteria or studies to validate the use of these tests to diagnose IR. Also note, insulin levels are notoriously difficult to measure accurately and, of course, in the face of advanced progression, namely, IGT or type 2 diabetes, insulin levels will not be high because of B cell exhaustion.

http://72.14.203.104/search?q=cache:...se+ratio&hl=en
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