I've been using the shampoo for some time a while ago and truthfully nothing happened.
Since then I've switched to Nizoral (2%) because there are studies that proved it works while Nioxin, well... they say on their bottle that 9 out of 10 people saw a difference (but how do I know it wasn't wishful thinking?). I still use Nioxin on days that I dont use Nizoral (since you can't really use that daily) beucase I have some left over. Since I've started Nizoral and Rogaine I'm seeing some hair starting to grow back 
Hope my experience is able to help you make a decision.
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Currently taking:
Magnesium, 500 mg
Chromium, 1000 mcg
Vitamin D, 2000 UI
Multivitamin
Soy Lecithin, 2400 mg
Saw Palmetto, 320 mg
Evening Primrose Oil, 2000 mg
Milk Thistle, 300 mg
Omega-3, 2000 mg
Minoxidil: 5% topical solution
Spearmint Tea (organic) 2 cups/day
Diet: Buckwheat (for DCI), Citrus and Legumes (D-pinitol), fish daily, a cup of chickpeas a day (Inositol).
Occasionally: a cup of carob or cinnamon tea
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Has anyone every used Nioxin? 
