pryncesslia

Hi, I started Metformin back in June. I was diagnosed IR with an insulin level of 33. After 6 weeks on 500MG of Metformin my insulin level was only down to 29. My doctor then increased my dosage up to 2000MG. My cycles immediately started to normalize (going from 47-73 days long to 25-32 days long). Another six weeks later and I just had my follow up blood tests. My insulin is now at 31. WTF! How can I be taking 2000MG of Metformin and have it not even impact my insulin level? And not that I'm complaining, but if my insulin level is still so high, then why are my cycles so much better? Help!

Lia

nobimbo

Did you take your Met the morning of your blood test? If not, then maybe that shows how your body reacts without Met (it overproduces insulin). If you took your Met the morning of your test, I really don't know how to answer your question. Met has been shown to help normalize cycles in non-IR women, so there's more to Met than just the insulin-sensitizing action.

Some women need to take another drug along with Met (such as Avandia, or Avandamet, which is a combo of both), or instead of it.

Linda

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dx pcos 1984, type II diabetes 2001, also hypertension
Met 2000mg since 2001, started Glucophage XR 4/22/04, then switched to Met ER 6/04; also: multi, Vit. C, Vit. E, B12/folic acid combo, fish oil & borage oil combo, garlic capsules, cinnamon, Vitex, calcium with magnesium/zinc, biotin, CoQ10, selenium,iron
Other meds: Verapamil and Altace(for blood pressure)
Started laser hair removal 7/29/03, completed 3/04 (it works!)
UAE for fibroid 3/24/03 and 3/16/04