Hi there and welcome to the board
I hope you can get to the bottom of your fatigue/depression. Here is a list of the most common symptoms of hypothyroidism. Following that is an article about the relationship between depression and PCOS which is very common, often due to hormonal imbalances:
68 Most Commonly Reported Symptoms of Hypothyroidism*
o Fatigue
o Swelling of eyelids
o Emotional instability
o Lethargy
o Dry skin
o Choking sensation
o Low endurance
o Dry mucous membranes
o Fineness of hair
o Slow speech
o Constipation
o Hair loss
o Slow thinking
o Weight gain unexplainably
o Blueness of skin
o Poor memory
o Paleness of lips
o Dry, thick, scaling skin
o Poor concentration
o Shortness of breath
o Dry, coarse, brittle hair
o Depression
o Swelling
o Paleness of skin
o Nervousness
o Hoarseness
o Puffy skin
o Anxiety
o Loss of appetite
o Puffy face or eyelids
o Worrying
o Prolonged menstrual bleeding
o Swelling of ankles
o Easy emotional upset
o Heavy menstrual bleeding
o Coarse skin
o Obsessive thinking
o Painful menstruation
o Brittle or thin nails
o Low motivation
o Low sex drive
o Dry ridges down nails
o Dizziness
o Impotence
o Difficulty in swallowing
o Sensation of cold
o Hearing loss
o Weakness
o Cold skin
o Rapid heart rate
o Vague body aches & pains
o Decreased sweating
o Pounding heart beat
o Muscle pain
o Heat intolerance
o Slow pulse rate
o Joint pain
o Non-restful sleep
o Pain at front of chest
o Numbness or tingling
o Insomnia
o Poor vision
o Protrusion of one or both eyeballs
o Thick tongue
o Weight loss
o Sparse eyebrows
o Swelling of face
o Wasting of tongue
http://www.drlowe.com/geninfo/hyposymptoms.htm
Depression and PCOS
Depression is a prominent characteristic of women who have polycystic ovary syndrome. Part of the depression stems from the emotional difficulty of being infertile, overweight, too hairy, or having acne, hair loss or some other disturbing symptom.
However, the primary cause of depression in PCOS appears to be hormonal in nature. A number of studies have shown a connection between a negative mood and elevated androgens, which are male hormones such as testosterone. In one interesting study, there was a correlation between the most intense depression and testosterone levels slightly above normal, but not when testosterone was low or extremely high.
Of course, depression is not limited to elevated testosterone. Depression has also been associated with insulin resistance and depressed thyroid function. Disturbed LH (luteinizing hormone) levels and rhythms have been found in depressed women compared to women who are not depressed. Disturbed LH is a primary reason why you don't ovulate. Abnormal estrogen and cortisol are additional hormonal factors connected to depression.
Women with mixed anxiety-depression disorder have high levels of homocysteine in the follicular and luteal phase of the menstrual cycle, and they have higher blood homocysteine levels as compared to healthy women. Women with PCOS commonly have elevated homocysteine, which is a byproduct of metabolic activity. Normally, homocysteine is broken down and made harmless. However, a poor diet that is deficient in calcium and B vitamins, and drugs such as metformin (Glucophage) help to elevate homocysteine.
All of the above factors for depression are common in PCOS women. There are additional factors that we won't go into here. But you can see that if you have PCOS and depression, you have a complex situation on your hands, a situation that does not have a simple solution.
The good news is that you can favorably alter your hormones and thus lift your depression at least to some extent with a healthy diet, regular exercise, stress management, selected nutritional supplements, and possibly medications. The diet would include plenty of whole, fresh vegetables, fresh fruit in moderation, fish, poultry, some other meats, nuts and seeds in moderation, greatly reduced consumption of grain products, and possible reduction of some legumes. (We'll go into greater detail in our upcoming PCOS Diet book). As for nutritional supplements, a high quality multi-vitamin/mineral would be a good place to start.
http://www.ovarian-cysts-pcos.com/news19.html
Linda
Hypothyroid, Symptoms of BCP, or clinical depression?? 
