Info on Inositol and how it can help PCOS

Lynn Parker · 04-21-2008, 03:28 PM

Hi Ladies

After searching through many web pages on PCOS and I came accross this, I thought this may be of interest to some of you:-

Inositol Improves Ovulation and Hormone Balance in PCOS Women

We have more very good news about inositol, a member of the B-vitamin family.

Two recent studies confirm earlier studies that inositol improves hormone balance and helps to restore normal cycles in women who have polycystic ovarian syndrome.

In the most recent study, from the University of Modena and Reggio Emilia in Italy, 25 overweight PCOS women were given 2 grams of inositol daily for 12 weeks. Menstrual cycles were restored in all women who did not have a normal cycle. Insulin resistance, a primary cause of polycystic ovary syndrome, was reduced.

The authors of the study conclude: "Myo-inositol administration improves reproductive axis functioning in PCOS patients, reducing the hyperinsulinemic state that affects LH secretion."

The other study is from the University of Perugia in Italy. It is a randomized, double blind, placebo-controlled clinical trial, which medical authorities say is the "gold standard" of medical studies.

The researchers divided 92 PCOS women into two groups. One group was given a placebo, while the other group received 4 grams of inositol daily.

Compared to the placebo group, the inositol group had a shorter time to first ovulation, and had a higher frequency of ovulation. The effect on ovarian follicles appeared to be rapid, starting in the first week of treatment.

In addition, the inositol group lost weight while the placebo group gained weight.

The researchers conclude: "These data support a beneficial effect of myo-inositol in women with oligomenorrhea and polycystic ovaries in improving ovarian function."

These and other medical studies suggest that therapeutic doses of inositol would be beneficial for ovulation, reduction of insulin resistance and luteinizing hormone, and possibly for weight loss.

If you do a search for Inositol there is more info

hope this helps

Lynn

LeilaniBaby · 04-21-2008, 04:49 PM

This sounds great. I read alot about inositol. I think its supposed to be converted to D chiro inositol, which PCOS women are usually deficient in.

I found this

D-Chiro Inositol and PCOS

You may have heard that d-chiro-inositol helps to treat polycystic ovarian syndrome. It is thought that it does this by improving insulin sensitivity.

Recent studies have suggested that women with PCOS may have insulin resistance and hyperinsulinemia due to a d-chiro inositol deficiency. D-chiro-inositol has been shown to influence the action of insulin. The amount of chiro-inositol in muscle has been shown to be lower in subjects with type 2 diabetes than in normal people.

A study from the Medical College of Virginia found that 1200 mg. of d-chiro-inositol daily had multiple beneficial effects in the treatment of 22 overweight PCOS women.(2) Not only did it improve the action of insulin, but 86% of the women ovulated during treatment with d-chiro-inositol compared to only 27% in the placebo group. Serum androgen (male hormone) and ovarian androgen production also decreased in the treatment group.

Another study showed similar results in lean PCOS women.(3)

However, there's one big problem: D-chiro-inositol is not commercially available, either as a drug or as a nutritional supplement.

Actually Chiral Balance is a company that produces D chiro inositol, but it is pricey: $150 for 1 month supply.
www.chiralbalance.com/store.html

Inositol and PCOS

Since d-chiro inositol is extremely expensive and not always readily available, what about ordinary inositol, which is readily available as a nutritional supplement? A recent study suggests that common inositol may be helpful for PCOS and polycystic ovaries.(4)

In this study at the laceType>UniversitylaceType> of laceName>PerugialaceName> in Italy, 136 PCOS women took inositol (100 mg., twice daily) for 14 weeks. Another group of PCOS women took placebo pills.

The ovulation frequency was significantly higher in the treated group (23%) compared with the placebo (13%). The time in which the first ovulation occurred was significantly shorter (23.6 days) compared with 41.8 days for the placebo group. The number of patients failing to ovulate was higher in the placebo group.

The effect of inositol on follicular maturation was rapid. Also, significant weight loss (and leptin reduction) was recorded in the inositol group, whereas in the placebo group had an increase in weight.

This study suggests a beneficial effect of inositol in improving ovarian function in women with irregular cycles and polycystic ovaries.

The website
www.ovarian-cysts-pcos.com/inositol.html

I just started the Insulite 4 days ago. I wonder if its okay to take both. Does anyone know?

Bertiebugg · 04-21-2008, 11:26 PM

It really does work. I have been taking Myoinositol for a little over 2 weeks and AF showed up!

Lynn Parker · 04-22-2008, 01:46 PM

Hi

Im going to do some more searching Im really interested in giving this a try.

hope2conceive · 04-23-2008, 04:24 PM

I ordered mine but it was backordered so, I'm going to go to the local healthfood store and see if they carry it so I can start it a.s.a.p.

I'll keep you updated as to how it goes on my end!
Luck to everyone!

Bertiebugg · 04-23-2008, 11:40 PM

If you're looking myoinositol I get mine at super suppliments http://www.supersup.com/

shyest · 04-25-2008, 05:04 PM

I ordered mine too so im excited to see if this works for me aswell.