We are justing starting a letrozole cycle..cd3-7. Today is cd 4. I'm going in for u/s on 1/23 to see how the letrozole is doing. Dr will then decide if I need a boost of repronex. Then I'll probably be trigging around 1/28.
Ok...so my question is: How many of you conceived twins or (gulp) or more w/this protocal? I'm very worried about conceiving multiples. I recently had my uterus remodeled (septum resection) and the doctor said a singleton would be best the first time around.
TIA!
sara (aka...Worry Wart)
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ME~31 DH~35 TTC~6 years 2 Angel babies~ To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
10/26/2007...Septum Resection Surgery for septated uterus
Praying this will be our answer!!
BFP on 6/13/2008!!
7/8/2008 U/S~Heart rate=144bpm!!
I was on 7.5 mg of femara and had the HCG trigger shot. I had 3 mature eggs at the u/s and the doc debated on whether to give me the full HCG trigger shot or half dose (since there was 3 egg already). He ended up giving me the full dose. When I got the BFP I was worried about multiples, but ended up only having 1.
In the past I didn't think I could have a reduction if I ended up with too many babies. But after reading posts on here by women that had reductions or woman that didn't, and then had issues, I now think I could do it. You've got to do what is best for you and your baby and if one at a time is best you'll find a way to get there. Take care and good luck!
__________________ Amanda (33) & DH (34)
ttc for 4 years
Femara,trigger shot,metformin,IUI-WORKED!
4/17/2008 Josie was born via c-section (vasa previa)
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Amanda...I never heard docs could prescribe half a dose of hcg. That's awesome way to control the eggs. Congrats on your little bean too!
lovesbabies...that's so sweet you are on here as a g'ma!! What a cutie grandbaby too!!! That's good to know that your dd had 2 follicles and had only one baby.
I'm really hoping that when i go on Wednesday the letrozole will be exactly what it needs to, and I'll be able to trigger in about a week. Praying that I won't need a boost from repronex or follistim which will increase the chance of multiples.
thanks for helping out a worry wart!
sara
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ME~31 DH~35 TTC~6 years 2 Angel babies~ To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
10/26/2007...Septum Resection Surgery for septated uterus
Praying this will be our answer!!
BFP on 6/13/2008!!
7/8/2008 U/S~Heart rate=144bpm!!
I was on 10mg Femara (yup 10mg) had 2 mature follies but there is only one in there! I think with careful monitoring you should be fine! GL to you!!!!!!
__________________ Me-Bre (27) Dh-Jon (29)
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BFP on 12/2/07!!! 10 mg Femara CD5-9.
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Haven't conceived...YET. But I took 7.5mg of Femara this cycle, and I have 3 follies. I'm scheduled for an IUI tomorrow, and hopefully I get a sticky bean during my 2ww!
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I did 1 cycle of femara/repronex, but I o'ed too early and didn't get to see how many follies I had. But by my #'s they guess 1.
I then did 3 cycles of femara 5 mg and gonal-f shots, I had 1 follie, then 2 follies then 1 follie. I conceived the 3rd cycle of IUI.
This last baby I lost was the same protocol, again 1 follie, but it was huge, 28 mm.
So it really depends on how you respond to the meds! Good luck to you!!
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Angel's ~ Sept/07, Dec/07 DS ~ 7
DD ~ 2.5
Twins ~ Born Feb 21st/09
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Amanda...I never heard docs could prescribe half a dose of hcg. That's awesome way to control the eggs.
I have not heard a half dose reduces the risk of multiples... it actually just lessens the risk of OHSS. Three follies is a low number of eggs to worry about OHSS with so I am not sure why a doc would consider a half dose of HCG.
There are, however, doctors who routinely use 5,000 units of HCG to trigger regardless of # of follies.
The weird thing about HCG I am told is there isn't really a known best dose. For some reason 10,000 units is standard because it works not because it is best - it's like if your TV picture was flipping and you whacked the TV 10 times and that fixed it, you'd just always whack it 10 times and never check if 1 or 5 or 7 times worked just as well. 5,000 units s used pretty often or even 2,500 if OHSS looks like a risk - and the eggs trigger just as well. I have read of a women who had twins with 2,500 unit trigger.
The sudden jolt of HCG is like an LH surge to your body, tells the ovaries to wrap up growing the eggs and spit 'em out. The more HCG you take, the longer it takes to leave your system, and the longer it hangs around, the greater the risk of OHSS.
Lupron is sometimes used to trigger an actual LH surge instead of HCG - practically eliminates the risk of OHSS.
FWIW I used a 6,000 unit HCG trigger and got pregnant with triplets and ended up in the hospital with OHSS.
Back to the original question - I think the risk of multiples with femara is about the same as with clomid. I think that is 10% or less chance of twins? And very small chance of anything greater. So not a huge chance but it CAN happen (and does happen)
Now of course it depends on how many follies you make... and then on luck. Bear in mind when everything is perfect there is a 20% chance of getting pregnant. So each egg has a 20% chance of fertilizing. So even if you have 3 eggs, it doesn't mean you will have triplets. I have read 3-4 eggs is the best for success, and beyond that it only increases the chance of multiples.
FWIW I had 10 eggs when I got triplets - my ovaries are over-eager on meds but won't do jack on their own. Stupid, lousy ovaries. BUT based on my odds - 3-4 would give you one baby. It's rare that all good follies seen on a scan all become fertilized eggs = viable babies. Not impossible, but rare.
Wishing you mono-baby dust, LOL!
eta let me clarify i did injections - menopur, similar to repronex! femara didn't do anything for me. To view links or images in this forum your post count must be 10 or greater. You currently have 0 posts. I wish I could pop a pill that would make me make just a few good eggs.
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We never talk of our lacking relationships
And how we're guilt-stricken, sobbing, with our heads on the floor
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Last edited by RunnerDuck; 01-23-2008 at 02:22 AM.
Letrozole or Femara....Anyone have multiples? 
