Polycystic ovary syndrome

Guidelines and free full text articles

General information

• Introduction
  to Polycystic ovary syndrome (Gynaecology Forum)


• New Perspectives
  in Polycystic Ovary Syndrome (American Society for Reproductive
  Medicine)


• PCOS Pavilion (OBGYN.net,
  US)


• Polycystic Ovarian
  Syndrome (Center for Applied Reproductive Science, US)


• Polycystic
  Ovarian Syndrome (Emedicine Inc., US)


• Polycystic
  Ovarian Syndrome (Emedicine Inc., US)


• Polycystic
  ovarian syndrome and infertility (Advanced Fertility Center
  of Chicago, US)


• Polycystic
  Ovarian Syndrome: Case Studies (Hospital Physician,
  US)


• Polycystic
  Ovary Syndrome (University of Cincinnati, US)


• Polycystic
  Ovary Syndrome (Vanderbilt University Medical Center, US)


• Polycystic
  Ovary Syndrome: It's Not Just Infertility (American Family
  Physician)


• Polycystic
  Ovary Syndrome: New Perspective on an Old Problem (Southern
  Medical Journal, US)


• Polycystic ovary
  syndrome: Pathogenesis and treatment over the short and long term
  (Cleveland Clinic Journal of Medicine, US)


• Polycystic
  ovarian syndrome: the metabolic syndrome comes to gynaecology (British
  Medical Journal)


• 
  Priorities in polycystic ovary syndrome (The Medical Journal
  of Australia)


• The
  Polycystic ovary syndrome page (Department of Computing
  Science, Umeå University, Sweden)

Adrenals

• Adrenal
  Androgen Excess in the Polycystic Ovary Syndrome: Sensitivity and
  Responsivity of the Hypothalamic-Pituitary-Adrenal Axis (The
  Journal of Clinical Endocrinology & Metabolism, US)


• 
  Adrenocortical Secretion of Dehydroepiandrosterone in Healthy Women:
  Highly Variable Response to Adrenocorticotropin (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Hormonal
  Findings in African-American and Caribbean Hispanic Girls With Premature
  Adrenarche: Implications for Polycystic Ovarian Syndrome (Pediatrics,
  US)


• The frequency
  of late-onset 21-hydroxylase and 11ß-hydroxylase deficiency in women
  with polycystic ovary syndrome (European Journal of Endocrinology)

Cardiovascular risk

• Altered
  Composition of High Density Lipoproteins in Women with the Polycystic
  Ovary Syndrome (The Journal of Clinical Endocrinology
  & Metabolism, US)


• Low
  Grade Chronic Inflammation in Women with Polycystic Ovarian Syndrome (The
  Journal of Clinical Endocrinology & Metabolism,
  US)


• 
  Polycystic Ovary Syndrome Is Associated With Endothelial Dysfunction
  (Circulation, US)

Epidemiology

• A
  Prospective Study of the Prevalence of the Polycystic Ovary Syndrome
  in Unselected Caucasian Women from Spain (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Prevalence
  of the Polycystic Ovary Syndrome in Unselected Black and White Women
  of the Southeastern United States: A Prospective Study (The
  Journal of Clinical Endocrinology & Metabolism, US)

Epilepsy

• 
  Characterization of Reproductive Endocrine Disorders in Women with
  Epilepsy (The Journal of Clinical Endocrinology
  & Metabolism, US)


• 
  Polycystic Ovarian Syndrome—Relationship to Epilepsy and Antiepileptic
  Drug Therapy (The Journal of Clinical Endocrinology
  & Metabolism, US)

Genetics

• A paradigm
  for finding genes for a complex human trait: Polycystic ovary syndrome
  and follistatin (Proceedings of the National Academy of Sciences,
  US)


• 
  CYTOCHROME P450, SUBFAMILY XIA; CYP11A (Online Mendelian
  Inheritance in Man, US)


• 
  CYTOCHROME P450, SUBFAMILY XIX; CYP19 (Online Mendelian
  Inheritance in Man, US)


• 
  Differential Activity of the Cytochrome P450 17alpha-Hydroxylase
  and Steroidogenic Acute Regulatory Protein Gene Promoters in Normal
  and Polycystic Ovary Syndrome Theca Cells (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Evidence
  for a genetic basis for hyperandrogenemia in polycystic ovary syndrome
  (Proceedings of the National Academy of Sciences, US)


• 
  Luteinizing Hormone Receptor, Steroidogenesis Acute Regulatory Protein,
  and Steroidogenic Enzyme Messenger Ribonucleic Acids Are Overexpressed
  in Thecal and Granulosa Cells from Polycystic Ovaries (The
  Journal of Clinical Endocrinology & Metabolism, US)


• 
  POLYCYSTIC OVARY SYNDROME 1; PCOS1 (Online Mendelian Inheritance
  in Man, US)


• 
  Screening for Mutations in the Steroidogenic Acute Regulatory Protein
  and Steroidogenic Factor-1 Genes, and in CYP11A and Dosage-Sensitive
  Sex Reversal-Adrenal Hypoplasia Gene on the X Chromosome, Gene-1
  (DAX-1), in Hyperandrogenic Hirsute Women (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Thirty-seven
  candidate genes for polycystic ovary syndrome: Strongest evidence
  for linkage is with follistatin (Proceedings of the National
  Academy of Sciences, US)

Hyperandrogenism

• Disruption
  of the Joint Synchrony of Luteinizing Hormone, Testosterone, and
  Androstenedione Secretion in Adolescents with Polycystic Ovarian
  Syndrome (The Journal of Clinical Endocrinology & Metabolism,
  US)


• Human
  sex hormone–binding globulin variants associated with hyperandrogenism
  and ovarian dysfunction (Journal of Clinical Investigation,
  US)


• 
  Prostate-Specific Antigen and Human Glandular Kallikrein 2 Are Markedly
  Elevated in Urine of Patients with Polycystic Ovary Syndrome (The
  Journal of Clinical Endocrinology & Metabolism,
  US)

Insulin, insulin resistance, diabetes

• A
  Fasting Glucose to Insulin Ratio Is a Useful Measure of Insulin
  Sensitivity in Women with Polycystic Ovary Syndrome (The
  Journal of Clinical Endocrinology & Metabolism, US)


• 
  
  A Unique Defect in the Regulation of Visceral Fat Cell Lipolysis in the
  Polycystic Ovary Syndrome as an Early Link to Insulin Resistance
  (Diabetes, US)


• 
  Defects in insulin receptor signaling in vivo in the polycystic
  ovary syndrome (PCOS) (Endocrinology and Metabolism,
  US)


• Defects
  of the insulin receptor substrate (IRS) system in human metabolic
  disorders (FASEB Journal, US)


• Effects
  of Methyltestosterone on Insulin Secretion and Sensitivity In Women (The
  Journal of Clinical Endocrinology & Metabolism,
  US)


• Glucose
  Intolerance in Obese Adolescents with Polycystic Ovary Syndrome:
  Roles of Insulin Resistance and ß-Cell Dysfunction and Risk of Cardiovascular
  Disease (The Journal of Clinical Endocrinology & Metabolism,
  US)


• 
  Heritability of Insulin Secretion and Insulin Action in Women with
  Polycystic Ovary Syndrome and Their First Degree Relatives (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Impaired
  Adipocyte Lipolysis in Nonobese Women with the Polycystic Ovary
  Syndrome: A Possible Link to Insulin Resistance? (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Insulin-Like
  Growth Factors Augment Steroid Production and Expression of Steroidogenic
  Enzymes in Human Fetal Adrenal Cortical Cells: Implications for
  Adrenal Androgen Regulation (The Journal of Clinical
  Endocrinology & Metabolism, US)


• 
  INSULIN RECEPTOR; INSR (Online Mendelian Inheritance in Man,
  US)


• Insulin
  Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications
  for Pathogenesis (Endocrine Reviews, US)


• Insulin
  Stimulates Testosterone Biosynthesis by Human Thecal Cells from
  Women with Polycystic Ovary Syndrome by Activating Its Own Receptor
  and Using Inositolglycan Mediators as the Signal Transduction System (The
  Journal of Clinical Endocrinology & Metabolism,
  US)


• Involvement
  of Ovarian Steroids in the Opioid-Mediated Reduction of Insulin
  Secretion in Hyperinsulinemic Patients with Polycystic Ovary Syndrome
  (The Journal of Clinical Endocrinology & Metabolism,
  US)


• Normal
  Endothelial Function Despite Insulin Resistance in Healthy Women
  with the Polycystic Ovary Syndrome (The Journal
  of Clinical Endocrinology & Metabolism, US)


• Ovarian
  Hyperandrogenism Is Associated with Insulin Resistance to Both Peripheral
  Carbohydrate and Whole-Body Protein Metabolism in Postpubertal Young
  Females: A Metabolic Study (The Journal of Clinical
  Endocrinology & Metabolism, US)


• 
  Phosphatidyl-Inositol-3 Kinase-Independent Insulin Action Pathway(s)
  in the Human Ovary (The Journal of Clinical Endocrinology
  & Metabolism, US)


• 
  Prevalence of Polycystic Ovary Syndrome Among Premenopausal Women
  With Type 2 Diabetes (Diabetes Care, US)


• 
  Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2
  in Moderate-to-Severe Insulin Resistance of Women With Polycystic
  Ovary Syndrome (Diabetes, US)


• 
  Saturated FFAs, Palmitic Acid and Stearic Acid, Induce Apoptosis
  in Human Granulosa Cells (Endocrinology, US)


• 
  Sex steroids and insulin resistance (Clinical Science, UK)


• Syndromes
  of Severe Insulin Resistance (The Journal of
  Clinical Endocrinology & Metabolism, US)


• 
  The Insulin-Related Ovarian Regulatory System in Health and Disease
  (Endocrine Reviews, US)


• Acanthosis nigricans
  
  
  
  • Acanthosis
    Nigricans (Emedicine Inc., US)
  
  
  • 
    ACANTHOSIS NIGRICANS (Online Mendelian Inheritance
    in Man, US)
  
  
  • 
    ACANTHOSIS NIGRICANS WITH MUSCLE CRAMPS AND ACRAL ENLARGEMENT (Online
    Mendelian Inheritance in Man, US)
  
  
  • 
    DIABETES MELLITUS, INSULIN-RESISTANT, WITH ACANTHOSIS NIGRICANS
    AND HYPERTENSION (Online Mendelian Inheritance
    in Man, US)
  
  
  • HAIR-AN
    Syndrome: A Multisystem Challenge (American Family
    Physician)
  
  
  • 
    RETINITIS PIGMENTOSA, DEAFNESS, MENTAL RETARDATION, AND HYPOGONADISM (Online
    Mendelian Inheritance in Man, US)
  
  
  
  


• Familial partial lipodystrophy
  
  
  
  • 
    LIPODYSTROPHY, FAMILIAL PARTIAL; FPLD (Online Mendelian
    Inheritance in Man, US)
  
  
  
  


• Seip syndrome
  
  
  
  • 
    BERARDINELLI-SEIP CONGENITAL LIPODYSTROPHY; BSCL (Online
    Mendelian Inheritance in Man, US)
  
  
  • 
    Normal Reproductive Function in Leptin-Deficient Patients with
    Lipoatropic Diabetes (The Journal of Clinical
    Endocrinology & Metabolism, US)
  
  
  
  

Obstructive sleep apnea

• 
  Increased Prevalence of Obstructive Sleep Apnea Syndrome in Obese
  Women with Polycystic Ovary Syndrome (The Journal of Clinical
  Endocrinology & Metabolism, US


• 
  Polycystic Ovary Syndrome Is Associated with Obstructive Sleep Apnea
  and Daytime Sleepiness: Role of Insulin Resistance (The
  Journal of Clinical Endocrinology & Metabolism, US)

Ovulatory disorders, pathophysiology

• Determinants
  of Abnormal Gonadotropin Secretion in Clinically Defined Women with
  Polycystic Ovary Syndrome (The Journal
  of Clinical Endocrinology & Metabolism, US)


• Low
  Levels of Follicle-Stimulating Hormone Receptor-Activation Inhibitors
  in Serum and Follicular Fluid from Normal Controls and Anovulatory
  Patients with or without Polycystic Ovary Syndrome (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Normal
  Ovulatory Women with Polycystic Ovaries Have Hyperandrogenic Pituitary-Ovarian
  Responses To Gonadotropin-Releasing Hormone-Agonist Testing
  (The Journal of Clinical Endocrinology & Metabolism,
  US)


• Polycystic
  Ovary Syndrome: Evidence for Reduced Sensitivity of the Gonadotropin-Releasing
  Hormone Pulse Generator to Inhibition by Estradiol and Progesterone
  (The Journal of Clinical Endocrinology & Metabolism,
  US)


• Premature
  Response to Luteinizing Hormone of Granulosa Cells from Anovulatory
  Women with Polycystic Ovary Syndrome: Relevance to Mechanism of
  Anovulation (The Journal of Clinical Endocrinology
  & Metabolism, US)


• 
  STEROID 5-ALPHA-REDUCTASE 1; SRD5A1 (Online Mendelian Inheritance
  in Man, US)


• Timing
  of Prenatal Androgen Excess Determines Differential Impairment in
  Insulin Secretion and Action in Adult Female Rhesus Monkeys (The
  Journal of Clinical Endocrinology & Metabolism, US)


• Use
  of a Gonadotropin-Releasing Hormone Antagonist as a Physiologic
  Probe in Polycystic Ovary Syndrome Assessment of Neuroendocrine
  and Androgen Dynamics (The Journal of Clinical
  Endocrinology & Metabolism, US)

Quality of life

• Development
  of a Health-Related Quality-of-Life Questionnaire (PCOSQ) for Women
  with Polycystic Ovary Syndrome (The Journal of
  Clinical Endocrinology & Metabolism, US)


• Diagnostic
  and treatment characteristics of polycystic ovary syndrome: descriptive
  measurements of patient perception and awareness from 657 confidential
  self-reports (BMC Women's Health, UK)

Treatment

• Polycystic
  ovary syndrome: a new direction in treatment (The Medical
  Journal of Australia)


• Clomiphene citrate
  
  
  
  • Decline
    in Insulin-Like Growth Factor I Levels after Clomiphene Citrate
    Does Not Correct Hyperandrogenemia in Polycystic Ovary Syndrome
    (The Journal of Clinical Endocrinology & Metabolism, US)
  
  
  • 
    Free Androgen Index and Leptin Are the Most Prominent Endocrine
    Predictors of Ovarian Response during Clomiphene Citrate Induction
    of Ovulation in Normogonadotropic Oligoamenorrheic Infertility
    (The Journal of Clinical Endocrinology & Metabolism, US)
  
  
  
  


• Flutamide
  
  
  
  • Hormonal
    Effects of Flutamide in Young Women with Polycystic Ovary Syndrome
    (The Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  • The
    Effect of a Pure Antiandrogen Receptor Blocker, Flutamide, on
    the Lipid Profile in the Polycystic Ovary Syndrome (The
    Journal of Clinical Endocrinology & Metabolism, US)
  
  
  
  


• Gonadotropins, pulsatile GnRH, GnRH analogues
  
  
  
  • Cohort
    Size Rather Than Follicle-Stimulating Hormone Threshold Level
    Determines Ovarian Sensitivity in Polycystic Ovary Syndrome
    (The Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  • Specific
    Factors Predict the Response to Pulsatile Gonadotropin-Releasing
    Hormone Therapy in Polycystic Ovarian Syndrome (The
    Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  • 
    The Recombinant Follicle Stimulating
    Hormone : A New Alternative for Induction of Ovulation and Treatment
    of Polycystic Ovary Syndrome (Geneva Foundation for Medical
    Education and Research, Switzerland)
  
  
  • The
    Rise of Estradiol and Inhibin B after Acute Stimulation with
    Follicle-Stimulating Hormone Predict the Follicle Cohort Size
    in Women with Polycystic Ovary Syndrome, Regularly Menstruating
    Women with Polycystic Ovaries, and Regularly Menstruating Women
    with Normal Ovaries (The Journal of Clinical
    Endocrinology & Metabolism, US)
  
  
  
  


• Metformin, insulin sensitizers
  
  
  
  • Decreased
    Serum Leptin Concentrations during Metformin Therapy in Obese
    Women with Polycystic Ovary Syndrome (The
    Journal of Clinical Endocrinology & Metabolism, US)
  
  
  • 
    Effect of Long-Term Treatment with Metformin Added to Hypocaloric
    Diet on Body Composition, Fat Distribution, and Androgen and
    Insulin Levels in Abdominally Obese Women with and without the
    Polycystic Ovary Syndrome (The Journal of Clinical
    Endocrinology & Metabolism, US)
  
  
  • 
    Effect of Metformin on Insulin-Like Growth Factor (IGF) I and
    IGF-Binding Protein I in Polycystic Ovary Syndrome (The
    Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  • 
    Insulin Reduction with Metformin Increases Luteal Phase Serum
    Glycodelin and Insulin-Like Growth Factor-Binding Protein 1
    Concentrations and Enhances Uterine Vascularity and Blood Flow
    in the Polycystic Ovary Syndrome (The Journal of
    Clinical Endocrinology & Metabolism, US)
  
  
  • 
    Metformin and intervention in polycystic ovary syndrome (Endocrine
    Society of Australia, Australian Diabetes Society and
    Australasian Paediatric Endocrine Group)
  
  
  • 
    Metformin Effects on Clinical Features, Endocrine and Metabolic
    Profiles, and Insulin Sensitivity in Polycystic Ovary Syndrome:
    A Randomized, Double-Blind, Placebo-Controlled 6-Month Trial,
    followed by Open, Long-Term Clinical Evaluation (The
    Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  • Treatment of Polycystic
    Ovary Syndrome with Insulin Lowering Medications (Atlanta
    Reproductive Health Centre, US)
  
  
  • Troglitazone
    Improves Defects in Insulin Action, Insulin Secretion, Ovarian
    Steroidogenesis, and Fibrinolysis in Women with Polycystic Ovary
    Syndrome (The Journal of Clinical
    Endocrinology & Metabolism, US)
  
  
  • 
    Troglitazone Improves Ovulation and Hirsutism in the Polycystic
    Ovary Syndrome: A Multicenter, Double Blind, Placebo-Controlled
    Trial (The Journal of Clinical Endocrinology
    & Metabolism, US)
  
  
  
  


• Ovarian drilling
  
  
  
  • 
    Early Pregnancy is elusive and robust (Early Pregnancy,
    US)
  
  
  • Mid-Follicular
    Phase Pulses of Inhibin B Are Absent in Polycystic Ovarian Syndrome
    and Are Initiated by Successful Laparoscopic Ovarian Diathermy:
    A Possible Mechanism Regulating Emergence of the Dominant Follicle (The
    Journal of Clinical Endocrinology & Metabolism,
    US)
  
  
  
  

Search

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See also

• Amenorrhea: links, Menstrual
  disorders: links, Hirsutism:
  links, Infertility: links


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