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Old 08-31-2003, 12:17 AM   #1 (permalink)
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Question Low Cholesterol

Does anyone have low cholesterol? I was looking over my lab test from May and didn't notice this before because the values are listed in different units. I converted them and my cholesterol is quite low and I'm a bit annoyed that my endo didn't seem to think there was a problem with this (don't worry, I checked the math, the numbers are LOW). Anyways, I'm having trouble finding resources and info about low cholesterol and its effects on the body, but I feel it must be important because sex hormones are made out of cholesterol. Does anyone have any info or experience with this? Thanks a lot.

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Old 08-31-2003, 09:32 AM   #2 (permalink)
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http://www.pslgroup.com/dg/fff8a.htm

http://www.ucdmc.ucdavis.edu/ucdhs/h...aineffect.html

http://www.healthandage.at/Home/gm=0!gc=9!gid6=2303

Consequences of Low Cholesterol Levels
The negative consequences of low cholesterol levels, whether actively lowered or naturally low, are the subject of ongoing debate.

Effects on Mortality Rate

In one study, men with the lowest cholesterol levels had the highest mortality rate, generally due to cancer and other, non-heart related diseases. An analysis of this study along with additional research suggests strongly that this higher death rate is almost totally due to lung cancer in smokers with low cholesterol -- not low cholesterol itself.

Depression and Risk for Violent Death

Some studies have found that cholesterol is important for the production of serotonin, a chemical in the brain that at low levels is associated with depression. Men with naturally low cholesterol levels also have low serotonin levels. Some evidence has reported a link between natural low natural cholesterol levels and negative emotional states, including depression. Some studies have even reported a higher rate of deaths from suicide, accidents, or violence, which could be related to negative emotional states. The following are some of examples of such studies:


In one study male psychiatric patients with cholesterol below 160 mg/dL had twice the normal rate of suicide and elderly men with low cholesterol levels had three times the normal risk of depression.
In a large 2001 Swedish study, violent behavior was linked with naturally low cholesterol levels. A 2000 study of patients with depression and bipolar disorders found lower cholesterol levels during specific manic or depressive episodes. The study suggested that mood states might produce low cholesterol levels, not vice versa. A 2001 study reported a modest increase in deaths from suicide, accident, or trauma in people who lowered their cholesterol with diet or with non-statin drugs. Importantly, numerous studies have reported no association between the use of cholesterol-lowering drugs (particularly statins) with depression or violent death. Some researchers have observed that people with low cholesterol levels due to medical conditions or alcoholism are often also deficient in dietary fats known as omega-3 fatty acid, which are found in oily fish. Low levels of omega-3 fatty acids are linked with depression and aggression. In fact, some studies in which cholesterol was lowered using diets that included omega-3 fatty acids reported less depression.

Clearly, any link between low cholesterol levels and emotional disorders is uncertain.

Hemorrhagic Stroke

People with overall cholesterol levels below 180 mg/dL may be at risk for hemorrhagic stroke (which is bleeding in the brain), particularly if they also have high blood pressure. It should be noted, however, that this type of stroke is much less common than ischemic stroke (which is caused by artery blockage and may be related to low HDL cholesterol).

The only info I could find concerning low cholesterol and hormones was in reference to men with high cholesterol having lower testesterone levels. Testerone supplementation was recommended to help bring down the cholesterol. Low testesterone was found in many men who had suffered heart attacks, and it was thought that testesterone is protective against heart attacks. I don't know if lower testesterone in women results in lower cholesterol, but it is interesting to think about. Here's the link that discusses this:

http://www.wellnessmd.com/lowmale.html

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Old 08-31-2003, 08:26 PM   #3 (permalink)
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Thanks, Linda

The last bit about testosterone and cholesterol is really interesting to me. If testosterone lowers cholersterol, maybe I have high testosterone levels. I will have to get that checked out. I can't seem to find much more about the interaction/relationship between cholesterol and hormones, even though I know it's there. Kind of annoying

Also, I read on mercola.com that mercola raised his cholesterol to normal levels with fish oil, and I've been taking that recently. It has definite positive effects on mood for me, so maybe my cholesterol has risen a bit in the past couple of months.

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