When I found out that I was preg. both my endo and my obgyn said to stay on the met. That was on April 3. This past Monday my obgyn said to stop taking it as I didn't need it anymore. He said the only reason I was on it was to ovulate and since it worked and I was pregnant he said to get off of them. The endo on the other hand said that women with PCOS should stay on their meds the entire time to lower the risk of complications. So my question is how many women stayed on met and who didn't. I am just trying to figure out who to listen to next time around the endo or the obgyn.
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Jana(24) Michael(29) To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.
Married 08-21-04
1st pg lost 4-12-06 @ 6 weeks Baby Hudson
2nd pg lost 11-01-06 @ 11 weeks, Arin Hudson
4 furbabies- 3 cats and 1 very spoiled dog.
BFP 9-28-07 Due June 11, 2008
Its a GIRL
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From everything I've been reading, a pcos woman should remain on Metformin, for at least the first trimester, because it does help cut down the risk of miscarriage.
As far as your doctor saying the Met was only to get you to ovulate so you could conceive - well that is a very misguided comment on his part. Metformin isn't considered a 'fertility' drug. It's a drug to help control insulin levels, and it's even taken by men. Insulin is the culprit for many pcosers, and Metformin has proven to be the "miracle" drug at controlling the symptoms, and more importantly attacking pcos at the "root" by regulating a woman's cycle.
I am very sorry for your loss. I'm no doctor, but my advice would be to remain on the Metformin next time you are pregnant for at least your first trimester. (This is what I am planning to do as well when I conceive again.)
Take care
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__________________ Stacia 31-DH 36 Married since April 1997 Angel baby twins Sept. 05 To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.
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Tested positive for antiphospholipid antibodies, Heparin/Aspirin therapy for next pregnancy
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So my question is how many women stayed on met and who didn't.
I stayed on it through about the 20-week mark. My OB had to pretty much pry the Metformin bottle out of my hand - I didn't want to stop taking it.
I did carry the pregnancy to term and should I have another successful pregnancy, I'll take Met till at least 20 weeks, whether my OB likes it or not! (I'm sure he'll let me do what I want in this regard, though...)
__________________ Lean cyster ~ M/c @ 10 wks after seeing heartbeat 8/04, m/c @ about 10 weeks after seeing heartbeat 8-09. 2 chemical PGs lost @ 4.5 wks 1/05 & 3/05. 4/05: Dx w/antiphospholipid antibody syndrome.
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I was told last week at my Maternal fetal medicine appointment that should I get pregnant I should not stop taking the Metformin until atleast 14 weeks reguardless of what I'm told by my GYN
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Misty Lynn Married to Richard since 4/02/05 I beat Type II Diabetes
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When I had asked my RE's nurse about staying on the met when I found out I was pg, she said yes, stay on it until I was through week 12 because it decreases the risk for m/c from 68% to 12% in PCOS moms. I asked if the higher m/c rate for non-met taking PCOS women was because of low progesterone, and she said yes, that's exactly it. However, my progesterone wound up being low anyway, so I've been on Prometrium since week 6.
I'm at 13 weeks on Tuesday, and I'm starting to wean myself off the met and progesterone supps. I'm only on 1000mg of met anyway since my GI tract can't handle the 1500mg my PCOS needs to regulate itself, so in my case being on the met didn't really help that much since I still got the low progesterone levels. I have a feeling if I could have done the 1500mg, then I wouldn't have needed the supps, but I honestly cannot spend the rest of my life in the bathroom. So, I did both for the first trimester and am going to stop in the next week or so.
People on my expecting thread said I could stop the met cold turkey, but I should wean myself off the progesterone.
Becky
__________________ Me 32, DH 37
DX: PCOS 4/05
DD#1 born 10/26/06, 7lbs. 1oz.
DD#2 born 6/25/08, 7lbs. even
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saluki, when you eventually stopped the Metformin, did you do it cold turkey, or gradually?
My OB said I could stop cold turkey, but I decided to wean myself off. I had been on 1500 mg/day (1 pill with each meal), so I took the 2 pills/day the next week, then 1 pill/day the week after that.
I'm not on Met right now and will probably go back on when we start TTC again. Not sure when that will be.
__________________ Lean cyster ~ M/c @ 10 wks after seeing heartbeat 8/04, m/c @ about 10 weeks after seeing heartbeat 8-09. 2 chemical PGs lost @ 4.5 wks 1/05 & 3/05. 4/05: Dx w/antiphospholipid antibody syndrome.
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I just met with a new RE and he said part of the reason for the disparity among doctors (stay on met, don't stay on met, stop at 12 weeks, go the whole time...) is because there are no US studies backing the benefits to met use in pregnancy. There is anectdotal evidence - which is not enough for the FDA but is enough for some doctors - and there are studies from other countries - which the FDA ignores. There will never be a US study because 1. no one wants to be a pregnant guines pig and 2. there is no money in it from the drug companies' point of view.
I *really* don't understand that one, there are SO many women with PCOS, how could there not be money in it to prove they can/should stay on met all 40 weeks?? But this is *not* the first time I have heard this argument and money makes the world go round so...
This RE is of the opinion that you should definately stay on it the first 12 weeks and then there may be benefits to staying on it the whole time. He says, though, you only see him the first 10-12 weeks, and then you're at the mercy of the OB, so... he thinks since I had one healthy full term pregnancy on met, it should be possible to convince an OB to let me stay on.
From my point of view, there is no LET. I have stockpiled met and I will not go off of it. When I got pregnant with my son, my endo said to go off the met - I said no way. My OB was OK with me staying on it. Then we moved and my new OB was OK with it up until 28 weeks at which point he didn't think it would hurt to stay on it but didn't think it would help, either.
All I know is I carried to term with no GD and if I get and stay pregnant again, I will do the same (stay on met the whole time)
This recent miscarriage, I was on met but I had a blighted ovum which can happen to anyone... Supposedly PCOS can worsen egg quality so maybe there was something I could have done but I doubt it. I was on met so what else could I do? Miscarrying as early as you did... it may have been the same thing. Did you ever see an embryo or heartbeat? I definately think you should stay on it next time, but don't beat yourself up thinking met could have saved this pregnancy. It helps, but women miscarry for many reasons, and met unfortunately doesn't address all of them. Sometimes we miscarry because there is something wrong with the egg or baby... this is natures way of taking care of things. But sometimes the baby is fine but our hormones are a little whacky - this is where met can help.
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"We've tried to wash our hands of all of this
We never talk of our lacking relationships
And how we're guilt-stricken, sobbing, with our heads on the floor
We fell through the ice when we tried not to slip..."
- the verve pipe
With my first pg, I went to the doc at 7w and had an u/s and saw a good strong heartbeat. I discussed my fear of m/c with my doc and he said now that we had seen the heartbeat, the risk dropped greatly. He told me to go off of my Met (1000mg/day). I stopped the Met, and sometime in the next week, my baby's heart stopped beating, and I m/c'd 3 weeks after that (when I should have been 11 weeks pg).
I was lucky enough to get pg again just 2 months after my m/c and that time my doc had me stay on the Met for my entire pregnancy. I stopped the Met at approx. 36 weeks, deleivered my baby at 37w4d, and had no milk supply issues whatsoever. I now have an 11 month old healthy baby boy (and I never developed GD during my pg).
When we start to ttc again, I will go back on my Met and insist I stay on it through at least the first trimester, but if I have my way, I'll be on it the entire time again.
I stayed on it. It's effective against M/C, gestational diabetes, pre-eclampsia, and PTL. Since we're at increased risk of all of these, and it hasn't been proven dangerous for babies, it was an easy decision for me.
BTW, if you PM me with your e-mail address, I'll send you some studies that show it's safe for babies, too!
Metformin 
