I take both met and fluoxetine (have for a couple of years now) and I have had no problems from taking the two together. I get my periods regularly now thanks to the met (and I ovulate), and the fluoxetine has been a lifesaver to get my depression under control. As for anti-depressants causing weight gain, it does not apply to fluoxetine. On the contrary, it's beneficial for weight loss. HTH!
Luv,
Dani
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