bhjmom

Hi everyone... I am currently on day 10 of starting Met and I am now up to 1500 mg. As of yesterday, I started getting a little tiredness in my legs. They feel weak and like jello. I feel slightly dizzy/off balance as well.

Luckily, the GI upset has not really bothered me yet. Is the muscle stuff and dizziness common? Why does it happen?

Charity

jlbrown122

Are you making sure that you are eating a good meal when you take your met? My re told me to make sure I eat a good meal with my met in order to keep from getting dizzy or weak. I have never had this problem, but was remembering what she told me about making sure I eat.

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Janet (31) DH (41) ttc 7 years
Miscarriage 1/19/1999 at 10 weeks
Met ER 2000 mg daily
HSG to be scheduled next cycle after af
Waiting on dh's SA results
Expecting to start Clomid after test results are in

Pattyannruss

Muscle pain and fatigue are symptoms of the met.
Some people adjust after time and it will go away. If it gets worse or doesn't go away in a week or so, you may need to adjust your dose.

I became very sensitive to it and had to finally stop it.

Try adding Potasium and see if that helps(does for most people)

Hang in there

Patty

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Tubal ligation syndrome(Sister of PCOS)

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nobimbo

The dizziness can be from lower blood sugar than you're used to (not necessarily hypoglycemia, but lower than your own normal) and/or dehydration. It's important to drink a lot of water and eat every few hours while on Met.

In regards to the muscle tiredness, it's mentioned a lot here and is common. Here is an explanation of why this happens:

Recent research suggests that Metformin may stimulate glucose uptake by muscles and inhibit glucose production by the liver by activating an enzyme, AMP-activated protein kinase which is present in muscle, liver, and heart cells. This enzyme is usually activated when exercise has burnt off cellular energy stores. So in a way, Metformin seems to trick the body into thinking it has exercised. This may be why it causes a small amount of weight loss and also results in elevated levels of lactate--the substance that makes your muscles ache the day after an exercise session.


Linda

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dx pcos 1984, type II diabetes 2001, also hypertension
Met 2000mg since 2001, started Glucophage XR 4/22/04, then switched to Met ER 6/04; also: multi, Vit. C, Vit. E, B12/folic acid combo, fish oil & borage oil combo, garlic capsules, cinnamon, Vitex, calcium with magnesium/zinc, biotin, CoQ10, selenium,iron
Other meds: Verapamil and Altace(for blood pressure)
Started laser hair removal 7/29/03, completed 3/04 (it works!)
UAE for fibroid 3/24/03 and 3/16/04