I don't know much about Actos in relation to PCOS, but I will post this which is from the Quick Look Drug Book that gives general info...hope this helps a little.
U.S./Canadian Brand Names
Actos™
Therapeutic Category
Antidiabetic Agent, Oral
Thiazolidinedione Derivative
Use
Type 2 diabetes, monotherapy: Adjunct to diet and exercise, to improve glycemic control
Type 2 diabetes, combination therapy with sulfonylurea, metformin, or insulin: When diet, exercise, and a single agent alone does not result in adequate glycemic control
Usual Dosage
Adults: Oral:
Monotherapy: Initial: 15-30 mg once daily; if response is inadequate, the dosage may be increased in increments up to 45 mg once daily; maximum recommended dose: 45 mg once daily
Combination therapy:
With sulfonylureas: Initial: 15-30 mg once daily; dose of sulfonylurea should be reduced if the patient reports hypoglycemia
With metformin: Initial: 15-30 mg once daily; it is unlikely that the dose of metformin will need to be reduced due to hypoglycemia
With insulin: Initial: 15-30 mg once daily; dose of insulin should be reduced by 10% to 25% if the patient reports hypoglycemia or if the plasma glucose falls to below 100 mg/dL. Doses greater than 30 mg/day have not been evaluated in combination regimens.
A 1-week washout period is recommended in patients with normal liver enzymes who are changed from troglitazone to pioglitazone therapy.
Dosage Forms
Tablet: 15 mg, 30 mg, 45 mg
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