Non-insulin resistant and taking Metformin

Lee825 · 11-22-2006, 12:19 AM

Based on an ultrasound and some blood work, my doctor has diagnosed me with PCOS. However, my insulin levels came back normal. My doctor prescribed me Metformin, which I began taking today. I read the Meformin Q&A on this thread and know that it can make non-insulin resistant women ovulate (I've only had 3 periods this year). However, most of the information out there regarding PCOS refers to insulin resistance.

Are there any women on this board who are non-insulin resistant who have had success with Metformin? My husband and I are TTC. I would appreciate any responses!

Amy2006 · 11-22-2006, 09:16 PM

I am also non insulin resistant and have been on met for almost three months. I am happy to say that this is the first month I have ovulated on day 15. My O days are usually on days 33-39. With a little patience, met is starting to work.

Amy

Lee825 · 11-22-2006, 11:02 PM

Thank you so much! If you don't mind, I have a few questions:

1. What dosage did you start out on and what dosage are you currently taking?

2. Have you experienced any side effects?

3. How did you know you were ovulating? Are you using Ovulation Predictor Kits or are you charting your temps and cervical mucus?

Thanks for your responses and time! It makes me feel so much better knowing that I'm not the only person who has PCOS and is non-insulin resistant. I'm very hopeful that the Metformin will work.

Amy2006 · 11-23-2006, 01:24 PM

Happy Thanksgiving!

I started on 1000mg and that is the dosage I am currently on. I have been very lucky to have not really had any side effects. Though, my tummy was a little upset the first few days and I have been feeling weepy. I used regular ovulation sticks for months but I never had a positive one, so my Dr had me buy the clear blue easy ovulation monitor. I am so glad I did, It was well worth the money. The monitor is much more reliable than those hard to read sticks.

Just know that it could take several months for the Met to start working on your cycles. What dosage are you taking? Are you having any side effects? Please feel free to ask me anything. I am very thankful to have finally met someone in the same place. Wishing you some peace of mind and a bucket full of baby dust.
Amy

Quote:

Originally Posted by Lee825

Thank you so much! If you don't mind, I have a few questions:

1. What dosage did you start out on and what dosage are you currently taking?

2. Have you experienced any side effects?

3. How did you know you were ovulating? Are you using Ovulation Predictor Kits or are you charting your temps and cervical mucus?

Thanks for your responses and time! It makes me feel so much better knowing that I'm not the only person who has PCOS and is non-insulin resistant. I'm very hopeful that the Metformin will work.

Lee825 · 11-23-2006, 08:57 PM

Happy Thanksgiving to you, too!

My doctor has started me on 500mg/day and every 3 weeks I will increase by 500mg/day until I am taking 2000mg of Metformin. I was asking about the side effects because so far, I haven't really had any. My theory was that maybe it's because my insulin levels are considered normal and the Metformin doesn't have much work to do. I'll wait another week or 2 before I really stick to that theory, though! Apparently, although I'm (we're) non-insulin resistant, my doctor thinks my ovaries may be sensitive to the amount of insulin in my body which makes me very hopeful that it will work.

It's interesting that you said you're feeling weepy, because I've been feeling a little moody. I chalked it up to other things, but if it continues at least I know it can have that effect. Of course, I'm also on Progesterone because my doctor wants me to have a period, which I haven't had in quite a while.

I've heard of the ovulation sticks, but not the monitor. I will have to look for it. Did you test only on certain days or every day? As I mentioned before, I'm not used to having regular cycles and since I'm hoping the Metformin will change that I was wondering when or how often to check if I'm ovulating.

Are you also TTC? If so, do you think you'll start Clomid w/the Met?

Lee825 · 11-23-2006, 08:58 PM

Oops! I sent before saying thank you again!!!!! It really does make me feel so much better to read about your experiences. I hope you had a great holiday with your family and friends.

Amy2006 · 11-26-2006, 12:32 AM

I hope you got my last post. I dont see it listed.

Lee825 · 11-26-2006, 06:54 PM

Hey Amy! I don't think I did get your last post. I only see 2 other posts.

hedyvrie · 11-26-2006, 09:05 PM

I ovulated after being on met for 3 months. My cycles are a perfect 28 days. Before Met, I never ovulated on my own. I just got my BFP the first month we tried. Met was all I had to take to conceive! I also charted so I knew the right days to bd, but I could not have done it without Met! Good luck to you

Lee825 · 11-26-2006, 11:41 PM

Wow! Congratulations! If you don't mind sharing, what doseage were you taking when you began and what doseage did you end up taking? Your story gives me so much hope!

latinsoulcyster · 11-27-2006, 01:24 AM

Hello there. I just wanted to drop in and give you some more hope. I started at 500mg and worked up to 1500mg. At the time, I wasn't insulin resistant. After 6 months, I got pregnant. My dd is 18 months old now and I'm back on it. This time, I am insulin resistant. So I'm now on 2000mg. I'm looking to have baby number 2!

Lee825 · 11-27-2006, 07:00 PM

Thank you so much latinsoulcyster! That gives me a lot of hope. I love hearing everyone's positive responses. Good luck to you on TTC #2!

Amy2006 · 11-27-2006, 10:34 PM

Heather and Maria,
Thank you for your inspiration!!

elwaldrop · 12-04-2006, 11:30 PM

I'm not IR and I'm on Met. I started a year ago at 1000mg/day of regular met. I got periods regularly for 2 or 3 months and then my cycles got longer and longer. I just started 2000mg/day of Met XR today hoping to have more normal cycles.

somedaysoon · 12-08-2006, 03:39 AM

am also non insulin resistant and have been on met for almost three months. I started with 500 and worked up to 2000mg. I still have no idea how to tell when I am ovulating because my LH surge is always high with the PCOS. does anyone know how to tell???