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Old 11-03-2009, 01:20 PM   #1 (permalink)
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Default OB wants me off Met at 20 weeks!?!?

My OB said she wants to take me off of metformin at 20 weeks. Isn't that kind of risky? Isn't metformin suppose to help prevent miscarriage in pcos? She says they do it with all their pregnant pcos patients. I feel very nervous about this. I also want to keep taking it after pregnancy as it's the only treatment I will be getting while breastfeeding, but they only use metformin for ttc.
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Old 11-03-2009, 01:27 PM   #2 (permalink)
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Mine wants me off at 12 weeks (and in fact would rather I wasn't taking it now). It makes me nervous too, but I think the risk of miscarriage due to the increased insulin is reduced after that?

I'm looking forward to hearing more input though.
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Old 11-03-2009, 01:41 PM   #3 (permalink)
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My OB had me stop the Metformin right when I found out I was pg...so I was like 4 weeks... The babies are fine and have been
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Old 11-03-2009, 01:43 PM   #4 (permalink)
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It's okay to come off of the Metformin. I've been off of it for about 7 weeks now and I was very concerned about coming off of it for the same reason. She explained that the Metformin later in the pregnancy is doing nothing for the baby. By this time, the placenta is working and the baby is getting the nourishment it needs. Your hormone levels should be good too. Try not to stress over it, but I can totally relate! Oh, and my RE wanted me off of it by 10-12 weeks, but I stretched out the dosage to my advantage
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Old 11-03-2009, 01:50 PM   #5 (permalink)
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i just weaned myself off. On the dr. recommendation. No point after the first tri. they say.

It prevents (maybe) miscarriage in early pregnancy...
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Old 11-03-2009, 02:04 PM   #6 (permalink)
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With my 1st pregnancy, my OB said I could stay on Met the entire pregnancy. That it would help prevent GD.

I stopped taking Met when DD was born because frankly, I was working full time and breastfeeding and just couldn't remember to take it. I hate stopping and then starting due to the initial diarrhea. So I haven't taken Met in 4.5 years.

I went to my OB yesterday and she said I should have been on it all these years to help prevent my PCOS symptoms.

And they also want to check my glucose early, which I should have had it done already, but I've put of it due to being sooooo tired lately. I don't know if they will want to put me on Met now.

I think I'm more worried now because I wasn't on Met when we conceived and I'm not on Met now. But so far my progesterone was within the limits. I just worry about my glucose now.

I wonder if you take your OB some information if it will help change their mind? I know that when we were TTC#1, I was always armed with information about Met and its benefits in TTC and pregnancy. I didn't need to use it though, but I was ready to fight!

Good luck!
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Old 11-03-2009, 02:20 PM   #7 (permalink)
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Instructed to only take it during my first trimester for the reason it could help prevent m/c. I did til' 12 weeks although my OB okayed til 14 weeks. I had horrible diahreah since I guess being pregnant and taking it made me super sensitive to sugary or fatty foods. After 14 weeks there isn't much documentation it helps prevent after that and what it could do to the fetus. It's a personal choice ultimately if you have enough to last through pregnancy. You should be fine either way.
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Old 11-03-2009, 02:32 PM   #8 (permalink)
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You are fine to stop at 20 weeks. The reduced miscarriage rate applies to the first trimester.
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Old 11-03-2009, 02:33 PM   #9 (permalink)
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I'm still taking 1,000mg to prevent GD. My OB wants me on it until I give birth.

I think all doctor's vary on their opinions about metformin and pregnancy. If you don't trust your doctor, get a second opinion.
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Old 11-03-2009, 03:49 PM   #10 (permalink)
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My OB had me stop at 20 weeks, and I asked a lot of questions about it...hopefully it can help you feel better.

First off, my understanding is that Met does not actually prevent GD. Rather, it masks the symptoms. So, while your glucose levels may look ok when you do early testing while on Met, they could be spiking throughout the day which is just as bad.

So, in order to determine if you have GD, they usually want the Met out of your system for a 4-6 weeks to get a good reading. Usually GTT testing is done around 26 weeks, which is how my OB chose 20 weeks to stop.

If you do end up with GD, there are better drugs to treat you with. My understanding is that they are more effective and/or have been tested on pregnant women for their potential effects.

Hope this helps!
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Old 11-03-2009, 04:03 PM   #11 (permalink)
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I'm still on it, my RE and OBGYN have told me to take it thru the pregnancy, but getting off of it wont have any issues at 20 weeks like everyone said your placenta has taken over by then, but also like they said it is a personal choice as well. There are articles that talks about how good it is to stay on it and articles that says not to.
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Old 11-03-2009, 05:43 PM   #12 (permalink)
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I concieved on Met, my ob wanted me off at 14 weeks. Everything has been fine, and baby is kicking like crazy
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Old 11-03-2009, 05:48 PM   #13 (permalink)
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Weaned last week during wk 12 and all is well. So happy to be off it because it made me sick and tired all the time!
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Old 11-03-2009, 11:47 PM   #14 (permalink)
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I think it really depends on the doctor. My ob/gyn doesn't want me to stop taking it at all if, or when we finally do get a BFP.
With my last pregnancy, my midwife, did want me to stop taking it, so I did, but then when I transferred care to a high risk ob because of complications, he said I should have continued taking it. I ended up being super close to getting GD. HTH, and good luck!
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Old 11-04-2009, 12:25 AM   #15 (permalink)
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With DD#1 I had a different Ob to start out with and they had me stop the Met at 14 Weeks. I did develop a mild case of GD.

With this DD#2 I have a midwife (who I saw for the second half of DD#1 pregnancy) and I have been on Met since DD#1 was born and have continued on it through out this pregnancy. I once again have a mild case of GD so for me it didn't prevent GD. But I see not only my midwife but also a perinatologist and an endocrinologist and none of them have wanted me to stop the Met. I think every Dr is different and ultimately you have to decide for yourself what you are comfortable doing and then fight to be able to do just that.
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