This is something that I ran across on Google News -
Article: Pantethine – Boost Your Brain, Cardio Health, Metabolism, and Detoxification
http://www.expertclick.com/NewsReleaseWire/default.cfm?Action=ReleaseDetail&ID=25274 Byron J Richards
February 12 2009
Pantethine is a nutrient that I knew nothing about prior to finding this article - I thought it had some interesting assertions about the possible benefits of Pantethine -- here are some excerpts that I found especially interesting:
Quote:
Pantethine can dramatically change your health and improve your metabolism. Pantethine, like no other nutrient, directly fuels the production Co-Enzyme A (CoA). CoA is a pivotal energy-broker molecule in your metabolism, used in at least seventy metabolic pathways involved in the metabolism of fat, cholesterol, carbohydrates, and amino acids
. . . .
Quote:
Pantethine is a derivative of vitamin B5 (pantothenic acid). Regular vitamin B5 must go through five enzymatic conversions before it can become CoA. Pantethine goes through one. In individuals with fatigue or metabolic problems, the conversion of regular vitamin B5 into CoA is reduced, even impaired.
. . . .
Quote:
pantethine helped increase the level of the anti-inflammatory essential fatty acids EPA and DHA, while simultaneously lowering the pro-inflammatory levels of arachidonic acid.
. . . .
Quote:
In a study of patients with high cholesterol 900 mg of pantethine per day was shown to lower total and LDL cholesterol by 13.5% and triglycerides by 30%. HDL levels were boosted by 10%.
. . . . .
Quote:
Weight Loss, Leptin, Adiponectin, and Fatty Liver Improvement
The development of a fatty liver as a result of weight gain marks a serious metabolic turning point that sets the stage for type II diabetes and serious metabolic problems. In one study sixteen patients with fatty liver received 600 mg pantethine per day. Their liver enzymes were cut in half (returning to normal) and their adiponectin levels were improved. Improving adiponectin means that there will be less insulin resistance and risk for type II diabetes as well as less inflammation coming out of stored fat.
. . . .
Quote:
Animal studies show that pantethine activates lipoprotein lipase, the enzyme within white adipose tissue that helps break down triglycerides so that fatty acids are available to use as fuel. This means that pantethine will directly support healthy fat metabolism within white adipose tissue, and as mentioned above this includes the boosting of adiponectin levels. The net result is to support health leptin function with stored fat. And by clearing triglycerides out of the blood, pantethine supports leptin getting into your brain more efficiently, meaning that pantethine helps overcome leptin resistance problems.
Another animal study has looked into this in even more detail. The hypothalamus gland is the key subconscious part of the brain that registers the leptin signal. When the leptin-center in the hypothalamus gland is damaged then obesity results, due to a breakdown in central regulation of metabolism by your nervous system. In this study a drug was used to induce damage to the hypothalamus gland resulting in obesity. Pantethine helped to offset the problems that were induced – resulting in lower food intake, less weight gain, better insulin and glucose levels, lower triglycerides, lower cholesterol and improved activation of lipoprotein lipase in white adipose tissue.
Does anyone have other info on Pantethine or possibly experences (good or bad) with using a Pantethine supplement?
[size=2]This is something that I ran across on Google News -
That information isn't 'news'. It's a press release. Please be careful to be specific about the type of information posted here. Stick to credible news and medical resources, or at least research who is behind any releases.
The author of that press release has received warning letters from the Department of Health and Human Services, Food and Drug Administration about 'claims' he makes...
