PCOS Links Genetic Info: http://www.defeatdiabetes.org/Articl...mone020820.htm
This page also has a lot of links at the bottom: http://www.ncbi.nlm.nih.gov/entrez/q...st_uids=184700 More Genetic Info: http://www.highbeam.com/library/docf...G%3AResult&ao= http://www.pnas.org/cgi/content/full/96/15/8573 http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=9843997 http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=9920059 There is sooo much info out there saying that PCOS is genetic, why do we keep trying to blame ourselves. Yes exercise, diet, and weight loss help some, but they certainly don’t cure all symptoms of PCOS. Does that mean I don't continue the struggle? No, I work out like a fiend, knowing it is helping some. I take my medications, exercise and work with a great Endocrinologist. I will the healthiest person I can be.
PCOS is very complex and different for everyone.
There are five types of PCOS:
Types of PCOS
Usually the diagnosis includes both anovulation and androgen (testosterone) excess but many related conditions have become lumped together in the literature under the term polycystic ovarian syndrome. Woman with polycystic ovaries on ultrasound do not all have androgen excess, but insulin resistance is manifest in equal frequencies whether or not there are elevated androgens (11). Because of this mixed clinical picture, those conditions all collected under the term polycystic ovarian syndrome in the medical literature may include:
Traditional PCOS -- anovulatory, increased androgens, no insulin resistance
Endocrine Syndrome X -- anovulatory, increased androgens, insulin resistance or type 2 diabetes
Non-Traditional PCOS --anovulatory, normal androgens, obese, insulin resistant or type 2 diabetes
Non-Traditional PCOS -- ovulatory, increased androgens, mild insulin resistance
Idiopathic Hirsutism -- ovulatory, increased androgens, no insulin resistance
High Insulin levels due to insulin resistance may be a primary cause. The insulin levels cause the increased androgen levels. In some cases, the insulin resistance is a genetic abnormality (12) . Some instances of polycystic ovarian syndrome associated with male pattern baldness are thought to be due to an autosomal dominant genetic defect (13) but it is important to note that this does not explain all cases (14). Since this is a syndrome that likely includes different categories of diseases, it is also likely that some instances are caused by genetic abnormalities while other instances are caused by environmental or as yet unknown conditions.
SOURCE:
http://www.wdxcyber.com/dxinf001.htm We really need to educate ourselves, our doctors and each other. . I did a search of:
Stein Leventhal chromosome 19 allele 8 of D19S884 PCOS
and so much info came up.
I just get tired of having to explain to Doctors that “No, really I do exercise and diet, my body doesn’t work with me”. I’m sure you may familiar with the look you get.
Enjoy your research and day.
PCOS Genetic Links 
