LeeDawson

Tuesday 22 August 2006

PCOS women at risk of gestational diabetes
Source: Diabetes Care 2006; 29: 1915-7

Comparing the incidence of gestational diabetes mellitus between women with and without a diagnosis of polycystic ovary syndrome.


Polycystic ovary syndrome (PCOS) patients have more than double the risk for developing gestational diabetes mellitus (GDM) of other women, research suggests.

The finding is based on data for a large multiethnic population of pregnant women in Northern California.

Joan Lo (Kaiser Permanente of Northern California, Oakland, USA) and colleagues identified 92,933 pregnant women who were screened for GDM and then searched outpatient databases to see whether they had been diagnosed with PCOS.

This showed that women with PCOS were older than those without PCOS or related symptoms and that they were more likely to be white and to have a multiple gestation. After adjusting for these differences, the researchers found that women with a diagnosis of PCOS had a 2.44 increased odds of developing GDM, compared with women without PCOS, and that those who had symptoms of the disease but did not qualify for an actual diagnosis had a 1.40-elevated risk. Both of these relationships were statistically significant.

Lo and team say that further research is now needed to clarify the role of "infertility treatment, glucoregulatory drugs, and other factors during preconception care that may impact GDM risk."

They add: "Studies are also needed to determine whether PCOS women might benefit from management to reduce GDM risk and whether such measures affect pregnancy outcome."

Posted: 21 August 2006
http://www.orgyn.com/en/news/2006/We...38951135787037