Pictures of Acanthosis Nigricans (ie Dark patches of skin)

KatCarney · 08-06-2008, 01:08 AM

[coverattach=1]What is acanthosis nigricans?

Acanthosis nigricans (AN) is a skin disorder characterised by darkening (hyperpigmentation) and thickening (hyperkeratosis) of the skin, occurring mainly in the folds of the skin in the armpit (axilla), groin and back of the neck.

Acanthosis nigricans is not a skin disease per se but a cutaneous sign of an underlying condition or disease.

There are two important types of acanthosis: benign and malignant. Although classically described as a sign of internal malignancy, this is very rare. Benign types, sometimes described as ‘pseudoacanthosis nigricans’ are much more common. [coverattach=2]

What is the treatment for acanthosis nigricans?

The primary aim of treatment is to correct the underlying disease process. Often correcting the underlying cause results in resolution of the lesions.

Correct hyperinsulinaemia through diet and medication
Lose weight with obesity-associated AN
Excise or treat underlying tumour
Stop offending medicines in drug-induced AN
In hereditary AN, lesions tend to enlarge gradually before stabilising and/or regressing on their own.

[coverattach=3]There is no specific treatment for AN. Treatments considered are used primarily to improve cosmetic appearance and include topical retinoids, dermabrasion and laser therapy.

source: http://dermnetnz.org/systemic/acanthosis-nigricans.html

DOWNLOAD PDF: http://dermnetnz.org/systemic/pdf/ac...-dermnetnz.pdf

KatCarney · 08-06-2008, 01:10 AM

HEre are some more images.

KatCarney · 08-06-2008, 01:13 AM

Treatments and drugs
There's no specific treatment for acanthosis nigricans. Treating any underlying conditions may cause the skin changes to fade, however. If you're overweight, losing excess pounds can help. Sometimes dietary changes are helpful, too.

Lightening affected areas
If you're concerned about the appearance of your skin, your doctor may prescribe a cream or lotion to help lighten the affected areas. Some of these lotions contain modified vitamin A products, such as tretinoin (Retin-A, others), or other medications. Sometimes oral medications, such as isotretinoin (Accutane, others), are helpful. Fish oil supplements also may be recommended. Dermabrasion or laser therapy may help reduce the thickness of certain affected areas.

source: http://www.mayoclinic.com/health/aca...ents-and-drugs