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Old 03-05-2006, 01:43 AM   #1 (permalink)
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Arrow Research on NPC vs Synthetic Progestins

I found this info on drugstore.com and figured i would share.
Quote:
The hormone, progesterone, is the natural equivalent of synthetic progestins and is closely related to estrogen. However, natural progesterone and synthetic progestins are structurally different and have differing effects in the body. Synthetic progestins may be useful for endometriosis and menorrhagia (prolonged or profuse menstrual flow) because of their specific effects on progesterone receptors in the brain and on the glandular response of the uterine lining. However, these same effects may be detrimental for women with PMS, and may be associated with increased symptoms, such as depression, headaches, and water retention. Thus, natural progesterone may be preferable to synthetic progestins for PMS.
“Natural” progesterone refers to the molecule that is identical in chemical structure to the progesterone produced in the body, even if the molecule is synthesized in a laboratory.Progestins are found in oral contraceptive pills and are used in conventional hormone replacement therapy.
As for not using wild yam...

Quote:
Wild yam contains precursors to progesterone (such as diosgenin) that can be converted through a chemical process in the laboratory into progesterone—the exact same molecule made in the human body. However, contrary to popular claims, the diosgenin in wild yams cannot be converted into progesterone in the body.21 22 Women who require progesterone should consult their physician and not rely on wild yam or other herbs.
I hope this helps!
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