My pdoc has just switched me from Buspar to Seroquel (in addition to the Celexa and Wellbutrin), and wants me on 100 mg. for now. When I looked up Seroquel, all I saw was for bipolar and schizophrenia, neither of which I am (I'm just garden-variety depression and dysthymia) - has anyone heard of Seroquel for depression?
Does it actually work? I've got a feeling my pdoc's running out of ideas for me. :
__________________ Tracy, 33
Childfree by choice
Kitties - Monty and Lexie
Finally sort-of dx PCOS 11/06
Major depression/dysthymia, in remission - as long as I can remember
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I have not taken seroquel for depression,per se. My shrink gave it to me to help me sleep (I'm sure part of my sleeping issues are anxiety related) And help me sleep it did-I was on a ridiculously small dose and I was a total zombie. Hopefully it works better for you than it did for me. Although I do get the impression my doc is running out of ideas too.(lamictal,seroquel,neurontin,klonopin,lunesta so far for sleep...now she wants me to try ambien or trazadone)
What symtpoms are you still experienceing taking (celxa, buspar and wellbutrin)?
Seroquel can help with depression but it has more of a "numbing" effect . Sometimes it can be perscribed in small doses to help you sleep as a PP said but in huge doses expect to sleep TONS. Trazadone is also a sleep aid and is much less potent but trazadone is almost comparable to large doses of melatonin (which is something our body produces naturally and it is OTC).
I'm not sure why your Dr. is perscribing Seroquel. Unless you are complaining of sleep issues but even then I would think 100mg is a lot at one time. I've heard of Seroquel being used in smaller doses for sleep issues and gradually increasing it over time (smallest dose = 25mg...largest is 800mg). The Celexa in high dosages along w/ the wellbutrin should be helping w/ the depression.
Good luck! If it were me I would inqure why he was giving me seroquel? Maybe it's possible to start at a lower dose and go from there?
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Buspar is typically used for anxiety, and Seroquel works very well on anxiety, so that might be the reason for using it (although imo your pdoc should be explaining to you why he's choosing the meds he is choosing so you can be involved in the decision.)
100mg does sound like a high starting dose, but I'm not a doctor so...
__________________ -diagnosed 1/2004
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i am bipolar type 2 (primarily depressed). when first diagnosed, my md had me on 100 mg twice daily. i was like a zombie. i slept and gained weight on it. like some of the other ladies mentioned, in small doses it is fantastic for sleep. i really don't see it being helpful for depression alone, unless you are super-anxious.
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I guess I should have explained more. I have been experiencing a lot of anxiety the last couple of months (more than I usually do) and have been having a lot of difficulty staying asleep. The Buspar wasn't doing anything for my anxiety, and for some reason my pdoc wasn't real keen on raising my Celexa further (I already take 20 mg. 2x/day) even after taking me off the Buspar (I understand why she didn't want to raise the Celexa and still have me on Buspar, with serotonin syndrome and all).
I have had blood pressure issues with trazadone (I normally run on the low side of normal, but after taking it it's not unheard of me to go up to 140-150 over 110), and I am not at all excited on going on something like Ambien which could potentially be addictive.
Anyhow, thanks for the knowledge.
__________________ Tracy, 33
Childfree by choice
Kitties - Monty and Lexie
Finally sort-of dx PCOS 11/06
Major depression/dysthymia, in remission - as long as I can remember
Trust me, I'm not having kids... in search of birth control again.... To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.
I work as a therapist and see lots of clients that are on seroquel. It's approved for bipolar illness but not just for depression.
But...
It is very bad for people with metabolic syndrome. It will make you gain weight and increase your insulin resistance. I strongly urge my clients who are overweight or have a history of diabetes in the family to take another medicene.
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Seroquel works for me! So this is an interesting discussion. I was really really really tired at first, but once I got used to the drug, fairly quickly, I was no longer dead tired. I was also dead tired from the depression, so being on the drug was actually an improvement! My pdoc says Seroquel is a "mild" antidepressant, with a big "mood stabilizer" factor. I could also tell I was a bit too "numb" on the first dose, and then dropped down to just 25 mg per day and felt really normal again. No big weight gain, no big loss either, sad to say!
I'm about to change pdocs, so would like to ask Nina, and others, what she suggests as better alternatives to Seroquel. (I've also read about the metabolism concerns associated with Seroquel.) If I change docs, it would be a good time to try other drugs. But if one is working, is it worth changing?
Disco, can't give you much advice, since you are on such a cocktail of drugs already. If you trust your doctor, I'd give the Seroquel a chance. I could tell right away that it helped me. What about the PCOS? Is that under control? Are you on met? First you need to stabilize your hormones, until that happens you'll continue to get wicked mood swings and no psych drug will likely help.
__________________ Age: 54, post-menopause Two daughters, ages 10 and 14, natural conception! One mc at 12 weeks Original dx: 1983 "androgen excess syndrome" Re dx: 2003 (ovaries now clear, weight under control)
had Laser Current Meds: Met, 850 2x daily Seroquel, 12.5 mg 2x daily (for depression, mood swings) Multi vit Fish oil, 500 mg 2x daily Magnesium and Calcium
Seroquel worked very well for me with anxiety and insomnia, but I felt very numb on it and so I came off it. my pdoc thinks perhaps once we get the lamictal established, it might be better for me to try another medication like seroquel instead of the current cymbalta + ambien combo.
__________________ -diagnosed 1/2004
-treating with diet and exercise
-mom to 5 furkids, Patrick the greyhound, Gretta and Samantha the rabbits, Sophie and Rosie the guinea pigs, and 4 guinea pigs waiting at the Bridge.
-working on a PhD in American History
Seroquel for depression? 
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