I have PCOS and was diagnosed last month with hypothyroidism. My doc put me on Sythroid (the lowest dose to start) and wanted me to up my dose of Metformin to 1500mg per day. Well, I had a really bad reaction to the mix of the two. It was like I had drank 50 pots of high test coffee. I really thought that I was losing it. I was up for most of the night and when I did manage to get some sleep, I had horrible nightmares. And let's add in that every noise was amplified to 10 along with paranoia. I had to take a day off of work because I couldn't function. I stopped the Metformin immediately!!!
I went to see the doc this week and she put me on Glumetza. So far, so good. She told me that the side effects that I experienced were not typical with the Metformin/Synthroid mix. I realize that trying to tweak your med's for these issues can be trying. But that was just not cool. I hope that no one else experiences that.
I have had no bad side effects at all with the Synthroid alone. But I have had some good ones!! The brain fog has gotten so much better.

I can actually function like I used to. It's taken some time, but I am starting to get back to my old self.
My friends have noticed that I am happy again. They haven't seen that in me in a long, long time. And on top of everything else, I turned 40 last week.

Things are just getting so much better.
I am over 200 lbs and only 5' tall. I am working on the weight thing, but I am not going to let it take over my life. Your true friends will love you for who you are and not what you look like. Take care and it will get better!!!!!

__________________
Lew
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Keepin' a Metal Heart... Old School Metal Forever!
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Two Fur babies - Roxxi & Phoebe
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PCOS - Years
Hypothyroidism - 1/07
Metformin 2000mg
"Why can't I steer the ship before it hits the storm? I've fallen to the sea, but still I swim for shore" "Skid Row - Slave to the Grind"
"Nobody can make you feel inferior without your permission" - Eleanor Roosevelt