Wednesday 14 March 2007
Trial assesses PCOS and diabetes link
Source: Imperial College London, UK
Looking at the link between polycystic ovary syndrome and insulin resistance.
A novel UK project aiming to understand the link between polycystic ovary syndrome (PCOS) and insulin resistance was launched this week.
Women with PCOS are known to be three times more likely to develop Type 2 diabetes than healthy women without the disorder, but the mechanisms behind this are not yet understood.
The new research scheme funded by the charity Well Being of Women intends to identify a defect in the insulin-signaling pathway in woman with PCOS.
Researchers from Imperial College London will look at how ovarian cells metabolize glucose in women with and without the syndrome.
Professor Stephen Franks commented: "PCOS gives rise to a range of symptoms, these may be very distressing not only because of problems with irregular periods and with fertility but also because of excess body hair, acne, or alopecia.
"We still do not fully understand the underlying cause or causes of PCOS but insulin resistance plays an important part in many patients."
Franks and his team hope that their work will unlock new data that will "help to devise new and more effective methods of treatment for this very common hormone problem."
Posted: 14 March 2007
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